Literature DB >> 2134323

Monochloroacetic acid exposure: a case report.

G D Kusch1, L P McCarty, J M Lanham.   

Abstract

Monochloroacetic acid exposure causes significant burns but can also be lethal following exposures of less than ten percent of body surface area. There have been two known survivors of significant monochloroacetic acid exposure. This is a case report of one of those survivors. The mechanism of toxicity is unknown, and attempts to relate monochloroacetic acid toxicity is to that of monofluoroacetic acid have yielded inconsistent results. The best mode of therapy is unclear, and no antidote has been proven effective, although ethanol and glycerol monoacetate have been suggested. The details of this case may be helpful to those faced with similar situations and to those investigating the toxicology of monochloroacetic acid.

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Year:  1990        PMID: 2134323

Source DB:  PubMed          Journal:  Pol J Occup Med        ISSN: 0860-6536


  3 in total

1.  Hepatic injury and gluconeogenesis after subcutaneous injection of monochloroacetic acid in rats.

Authors:  Yumi Toshina; Tomotaro Dote; Kan Usuda; Hiroyasu Shimizu; Mika Tominaga; Koichi Kono
Journal:  Environ Health Prev Med       Date:  2004-03       Impact factor: 3.674

2.  Exposure Characterization of Haloacetic Acids in Humans for Exposure and Risk Assessment Applications: An Exploratory Study.

Authors:  Shahid Parvez; Jeffrey L Ashby; Susana Y Kimura; Susan D Richardson
Journal:  Int J Environ Res Public Health       Date:  2019-02-06       Impact factor: 3.390

3.  Skin burns from monochloroacetic acid leak in a chemical plant: a case report.

Authors:  Yiming Tao; Tingting Liu; Xiangdong Jian
Journal:  Arh Hig Rada Toksikol       Date:  2020-06-29       Impact factor: 2.078

  3 in total

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