| Literature DB >> 21339636 |
Lucienne Chatenoud1, Jean-François Bach.
Abstract
Hepatitis A virus (HAV) usually results in asymptomatic infection or mild disease, but in a small subset of patients it can lead to severe disease and even liver failure. In this issue of the JCI, Kim et al. identify a polymorphism associated with this increased disease risk in the gene that encodes the HAV receptor--TIM1. Importantly, this TIM1 gene polymorphism protects from the development of atopic diseases in HAV-seropositive individuals.Entities:
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Year: 2011 PMID: 21339636 PMCID: PMC3049371 DOI: 10.1172/JCI46418
Source DB: PubMed Journal: J Clin Invest ISSN: 0021-9738 Impact factor: 14.808