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Literature DB >> 21338082

Diversity-oriented approach to pyrrole-imidazole alkaloid frameworks.

Manojkumar R Bhandari¹, Muhammed Yousufuddin, Carl J Lovely.

Abstract

An exploration of imidazolylpropargyl amides as linchpin synthons for the construction of a diverse array of heterocyclic frameworks, many of which are related to those found in the oroidin derived alkaloids, is described. One such intermediate has been used in a formal total synthesis of cyclooroidin.

Entities: Chemical Gene

Mesh：

Substances：

Year: 2011 PMID： 21338082 PMCID： PMC3099625 DOI： 10.1021/ol200067e

Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005

31 in total

1. Extending Pummerer reaction chemistry: application to the assembly of the pentacyclic core of dibromopalau'amine.

Authors: Ken S Feldman; Ahmed Yimam Nuriye
Journal: Org Lett Date: 2010-10-15 Impact factor: 6.005

2. Gold-catalyzed organic reactions.

Authors: A Stephen K Hashmi
Journal: Chem Rev Date: 2007-06-20 Impact factor: 60.622

3. Stylissadines A and B: the first tetrameric pyrrole-imidazole alkaloids.

Authors: Achim Grube; Matthias Köck
Journal: Org Lett Date: 2006-10-12 Impact factor: 6.005

4. Revisiting the Kinnel-Scheuer hypothesis for the biosynthesis of palau'amine.

Authors: Zhiqiang Ma; Jianming Lu; Xiao Wang; Chuo Chen
Journal: Chem Commun (Camb) Date: 2010-09-16 Impact factor: 6.222

5. Total synthesis of all (-)-Agelastatin alkaloids.

Authors: Mohammad Movassaghi; Dustin S Siegel; Sunkyu Han
Journal: Chem Sci Date: 2010-01-01 Impact factor: 9.825

6. New method for preparation of coumarins and quinolinones via Pd-catalyzed intramolecular hydroarylation of C-C triple bonds.

Authors: C Jia; D Piao; T Kitamura; Y Fujiwara
Journal: J Org Chem Date: 2000-11-03 Impact factor: 4.354

7. Palladium-catalyzed dynamic kinetic asymmetric transformations of vinyl aziridines with nitrogen heterocycles: rapid access to biologically active pyrroles and indoles.

Authors: Barry M Trost; Maksim Osipov; Guangbin Dong
Journal: J Am Chem Soc Date: 2010-11-10 Impact factor: 15.419

Diversity-oriented approach to pyrrole-imidazole alkaloid frameworks.

1. Extending Pummerer reaction chemistry: application to the assembly of the pentacyclic core of dibromopalau'amine.

2. Gold-catalyzed organic reactions.

3. Stylissadines A and B: the first tetrameric pyrrole-imidazole alkaloids.

4. Revisiting the Kinnel-Scheuer hypothesis for the biosynthesis of palau'amine.

5. Total synthesis of all (-)-Agelastatin alkaloids.

6. New method for preparation of coumarins and quinolinones via Pd-catalyzed intramolecular hydroarylation of C-C triple bonds.

7. Palladium-catalyzed dynamic kinetic asymmetric transformations of vinyl aziridines with nitrogen heterocycles: rapid access to biologically active pyrroles and indoles.

8. Nagelamides Q and R, novel dimeric bromopyrrole alkaloids from sponges Agelas sp.

9. Total synthesis of the putative structure of nagelamide D.

10. Total synthesis of palau'amine.

1. Preparation and Diels-Alder reactions of 1'-heterosubsituted vinylimidazoles.