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Literature DB >> 20041464

Total synthesis of palau'amine.

Ian B Seiple¹, Shun Su, Ian S Young, Chad A Lewis, Junichiro Yamaguchi, Phil S Baran.

Abstract

Entities: Chemical Disease Gene

Mesh：

Substances：

Year: 2010 PMID： 20041464 PMCID： PMC3367661 DOI： 10.1002/anie.200907112

Source DB: PubMed Journal: Angew Chem Int Ed Engl ISSN： 1433-7851 Impact factor: 15.336

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46 in total

1. Spirocycloisomerization of tethered alkylidene glycocyamidines: synthesis of a base template common to the palau'amine family of alkaloids.

Authors: Hugo Garrido-Hernandez; Masakazu Nakadai; Marc Vimolratana; Qingyi Li; Thomas Doundoulakis; Patrick G Harran
Journal: Angew Chem Int Ed Engl Date: 2005-01-21 Impact factor: 15.336

2. EVALUATION OF STRATEGIES FOR THE SYNTHESIS OF THE GUANIDINE HEMIAMINAL PORTION OF PALAU'AMINE.

Authors: Brian A Lanman; Larry E Overman
Journal: Heterocycles Date: 2006-12-31 Impact factor: 0.831

3. Enantiospecific total syntheses of kapakahines B and F.

Authors: Timothy Newhouse; Chad A Lewis; Phil S Baran
Journal: J Am Chem Soc Date: 2009-05-13 Impact factor: 15.419

4. Stable 5-substituted cyclopentadienes for the Diels-Alder cycloaddition and their application to the synthesis of palau'amine.

Authors: Jonathan Hudon; Timothy A Cernak; James A Ashenhurst; James L Gleason
Journal: Angew Chem Int Ed Engl Date: 2008 Impact factor: 15.336

5. Regiocontrol in Mn(III)-mediated oxidative heterobicyclizations: access to the core skeletons of oroidin dimers.

Authors: Xianghui Tan; Chuo Chen
Journal: Angew Chem Int Ed Engl Date: 2006-06-26 Impact factor: 15.336

6. Direct coupling of indoles with carbonyl compounds: short, enantioselective, gram-scale synthetic entry into the hapalindole and fischerindole alkaloid families.

Authors: Phil S Baran; Jeremy M Richter
Journal: J Am Chem Soc Date: 2004-06-23 Impact factor: 15.419

7. Enantioselective total synthesis of (+)-dibromophakellstatin.

Authors: Karine G Poullennec; Daniel Romo
Journal: J Am Chem Soc Date: 2003-05-28 Impact factor: 15.419

8. Density functional theory guided design of exo-selective dehydroalanine dienophiles for application toward the synthesis of palau'amine.

Authors: Timothy A Cernak; James L Gleason
Journal: J Org Chem Date: 2007-12-08 Impact factor: 4.354

9. Massadine, a novel geranylgeranyltransferase type I inhibitor from the marine sponge Stylissa aff. massa.

Authors: Shinichi Nishimura; Shigeki Matsunaga; Mitsuyoshi Shibazaki; Kenichi Suzuki; Kazuo Furihata; Rob W M van Soest; Nobuhiro Fusetani
Journal: Org Lett Date: 2003-06-26 Impact factor: 6.005

10. Oxidative rearrangement of imidazoles with dimethyldioxirane.

Authors: Carl J Lovely; Hongwang Du; Yong He; H V Rasika Dias
Journal: Org Lett Date: 2004-03-04 Impact factor: 6.005

40 in total

1. Lessons and revelations from biomimetic syntheses.

Authors: Mina Razzak; Jef K De Brabander
Journal: Nat Chem Biol Date: 2011-11-15 Impact factor: 15.040

Review 2. Constructing molecular complexity and diversity: total synthesis of natural products of biological and medicinal importance.

Authors: K C Nicolaou; Christopher R H Hale; Christian Nilewski; Heraklidia A Ioannidou
Journal: Chem Soc Rev Date: 2012-06-28 Impact factor: 54.564

6. Rapid access to the core skeleton of the [3 + 2]-type dimeric pyrrole-imidazole alkaloids by triplet ketone-mediated C-H functionalization.

Authors: Lin You; Chuo Chen
Journal: Tetrahedron Date: 2017-12-15 Impact factor: 2.457

Total synthesis of palau'amine.

1. Spirocycloisomerization of tethered alkylidene glycocyamidines: synthesis of a base template common to the palau'amine family of alkaloids.

2. EVALUATION OF STRATEGIES FOR THE SYNTHESIS OF THE GUANIDINE HEMIAMINAL PORTION OF PALAU'AMINE.

3. Enantiospecific total syntheses of kapakahines B and F.

4. Stable 5-substituted cyclopentadienes for the Diels-Alder cycloaddition and their application to the synthesis of palau'amine.

5. Regiocontrol in Mn(III)-mediated oxidative heterobicyclizations: access to the core skeletons of oroidin dimers.

6. Direct coupling of indoles with carbonyl compounds: short, enantioselective, gram-scale synthetic entry into the hapalindole and fischerindole alkaloid families.

7. Enantioselective total synthesis of (+)-dibromophakellstatin.

8. Density functional theory guided design of exo-selective dehydroalanine dienophiles for application toward the synthesis of palau'amine.

9. Massadine, a novel geranylgeranyltransferase type I inhibitor from the marine sponge Stylissa aff. massa.

10. Oxidative rearrangement of imidazoles with dimethyldioxirane.

1. Lessons and revelations from biomimetic syntheses.

Review 2. Constructing molecular complexity and diversity: total synthesis of natural products of biological and medicinal importance.

3. Natural-product synthesis: stitching together palau'amine.

4. Palau'amine and related oroidin alkaloids dibromophakellin and dibromophakellstatin inhibit the human 20S proteasome.

5. Synthetic Studies on Palau'amine. Construction of the Cyclopentane Core via an Asymmetric 1,3-Dipolar Cycloaddition.

6. Rapid access to the core skeleton of the [3 + 2]-type dimeric pyrrole-imidazole alkaloids by triplet ketone-mediated C-H functionalization.

7. Chemists crack complex compound.

Review 8. Natural products synthesis: enabling tools to penetrate Nature's secrets of biogenesis and biomechanism.

9. Asymmetric synthesis of ageliferin.

Review 10. Natural products: a continuing source of novel drug leads.