Literature DB >> 21338078

ESIPT-mediated photocycloadditions of 3-hydroxyquinolinones: development of a fluorescence quenching assay for reaction screening.

Bing Xia1, Baudouin Gerard, Danielle M Solano, Jiandi Wan, Guilford Jones, John A Porco.   

Abstract

Irradiation of 1,2-dimethyl-3-hydroxyquinolinone (DMQ) leads to excited state intramolecular proton transfer (ESIPT) generating a 3-oxidoquinolinium species which undergoes [3 + 2] photocycloaddition with dipolarophiles. A parallel, fluorescence quenching assay using a microplate format has been developed to evaluate fluorescence quenching of this species with a range of dipolarophiles.

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Year:  2011        PMID： 21338078      PMCID： PMC3055927          DOI： 10.1021/ol200032f

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  14 in total

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4.  Biomimetic photocycloaddition of 3-hydroxyflavones: synthesis and evaluation of rocaglate derivatives as inhibitors of eukaryotic translation.

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6.  Steric control of the excited-state intramolecular proton transfer in 3-hydroxyquinolones: steady-state and time-resolved fluorescence study.

Authors:  Dmytro A Yushchenko; Volodymyr V Shvadchak; Andrey S Klymchenko; Guy Duportail; Vasyl G Pivovarenko; Yves Mély
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Authors:  Shaun R Stauffer; John F Hartwig
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Authors:  Warren G Lewis; Fernando G Magallon; Valery V Fokin; M G Finn
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9.  A fluorogenic aldehyde bearing a 1,2,3-triazole moiety for monitoring the progress of aldol reactions.

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10.  Design and use of fluorogenic aldehydes for monitoring the progress of aldehyde transformations.

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  6 in total

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Review 2.  Contemporary screening approaches to reaction discovery and development.

Authors:  Karl D Collins; Tobias Gensch; Frank Glorius
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Journal:  Synthesis (Stuttg)       Date:  2015-01       Impact factor: 3.157

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Journal:  J Am Chem Soc       Date:  2019-07-30       Impact factor: 15.419

5.  Synthesis of Aza-Rocaglates via ESIPT-Mediated (3+2) Photocycloaddition.

Authors:  Wenyu Wang; Regina Cencic; Luke Whitesell; Jerry Pelletier; John A Porco
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6.  Tandem dienone photorearrangement-cycloaddition for the rapid generation of molecular complexity.

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  6 in total

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