Literature DB >> 20687060

Biomimetic photocycloaddition of 3-hydroxyflavones: synthesis and evaluation of rocaglate derivatives as inhibitors of eukaryotic translation.

Stéphane P Roche1, Regina Cencic, Jerry Pelletier, John A Porco.   

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Year:  2010        PMID: 20687060      PMCID: PMC3611328          DOI: 10.1002/anie.201003212

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN: 1433-7851            Impact factor:   15.336


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  25 in total

1.  Femtosecond dynamics on excited-state proton/charge-transfer reaction in 4'-N,N-diethylamino-3-hydroxyflavone. The role of dipolar vectors in constructing a rational mechanism.

Authors:  Pi-Tai Chou; Shih-Chieh Pu; Yi-Ming Cheng; Wei-Shan Yu; Yueh-Chi Yu; Fa-Tsai Hung; Wei-Ping Hu
Journal:  J Phys Chem A       Date:  2005-05-05       Impact factor: 2.781

2.  The oxyallyl diradical: observation of the singlet and triplet state by negative-ion photoelectron spectroscopy.

Authors:  Holger F Bettinger
Journal:  Angew Chem Int Ed Engl       Date:  2010       Impact factor: 15.336

3.  Enantioselective synthesis of the complex rocaglate (-)-silvestrol.

Authors:  Baudouin Gerard; Regina Cencic; Jerry Pelletier; John A Porco
Journal:  Angew Chem Int Ed Engl       Date:  2007       Impact factor: 15.336

4.  Electrochromic modulation of excited-state intramolecular proton transfer: the new principle in design of fluorescence sensors.

Authors:  Andrey S Klymchenko; Alexander P Demchenko
Journal:  J Am Chem Soc       Date:  2002-10-16       Impact factor: 15.419

Review 5.  Potential of cyclopenta[b]benzofurans from Aglaia species in cancer chemotherapy.

Authors:  Soyoung Kim; Angela A Salim; Steven M Swanson; A Douglas Kinghorn
Journal:  Anticancer Agents Med Chem       Date:  2006-07       Impact factor: 2.505

6.  Accumulated proton-donating ability of solvent molecules in proton transfer.

Authors:  Sun-Young Park; Du-Jeon Jang
Journal:  J Am Chem Soc       Date:  2010-01-13       Impact factor: 15.419

7.  Nazarov cyclization initiated by peracid oxidation: the total synthesis of (+/-)-rocaglamide.

Authors:  John A Malona; Kevin Cariou; Alison J Frontier
Journal:  J Am Chem Soc       Date:  2009-06-10       Impact factor: 15.419

8.  Functional characterization of IRESes by an inhibitor of the RNA helicase eIF4A.

Authors:  Marie-Eve Bordeleau; Ayaka Mori; Monika Oberer; Lisa Lindqvist; Louisa S Chard; Tatsuo Higa; Graham J Belsham; Gerhard Wagner; Junichi Tanaka; Jerry Pelletier
Journal:  Nat Chem Biol       Date:  2006-03-12       Impact factor: 15.040

9.  Synthetic analogue of rocaglaol displays a potent and selective cytotoxicity in cancer cells: involvement of apoptosis inducing factor and caspase-12.

Authors:  Frédéric Thuaud; Yohann Bernard; Gülen Türkeri; Ronan Dirr; Geneviève Aubert; Thierry Cresteil; Aurélie Baguet; Catherine Tomasetto; Yuri Svitkin; Nahum Sonenberg; Canan G Nebigil; Laurent Désaubry
Journal:  J Med Chem       Date:  2009-08-27       Impact factor: 7.446

10.  Wittig reactions in water media employing stabilized ylides with aldehydes. Synthesis of alpha,beta-unsaturated esters from mixing aldehydes, alpha-bromoesters, and Ph3P in aqueous NaHCO3.

Authors:  Amer El-Batta; Changchun Jiang; Wen Zhao; Robert Anness; Andrew L Cooksy; Mikael Bergdahl
Journal:  J Org Chem       Date:  2007-06-09       Impact factor: 4.354

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  25 in total

1.  Synthesis of rocaglamide hydroxamates and related compounds as eukaryotic translation inhibitors: synthetic and biological studies.

Authors:  Christina M Rodrigo; Regina Cencic; Stéphane P Roche; Jerry Pelletier; John A Porco
Journal:  J Med Chem       Date:  2011-12-19       Impact factor: 7.446

2.  Emerging therapeutics targeting mRNA translation.

Authors:  Abba Malina; John R Mills; Jerry Pelletier
Journal:  Cold Spring Harb Perspect Biol       Date:  2012-04-01       Impact factor: 10.005

3.  Total synthesis of (±)-rocaglamide via oxidation-initiated Nazarov cyclization.

Authors:  John A Malona; Kevin Cariou; William T Spencer; Alison J Frontier
Journal:  J Org Chem       Date:  2012-01-26       Impact factor: 4.354

Review 4.  Chemical probes and drug leads from advances in synthetic planning and methodology.

Authors:  Christopher J Gerry; Stuart L Schreiber
Journal:  Nat Rev Drug Discov       Date:  2018-04-13       Impact factor: 84.694

Review 5.  Chemistry and biology of rocaglamides (= flavaglines) and related derivatives from aglaia species (meliaceae).

Authors:  Sherif S Ebada; Neil Lajkiewicz; John A Porco; Min Li-Weber; Peter Proksch
Journal:  Prog Chem Org Nat Prod       Date:  2011

6.  Enantioselective photocycloaddition of 3-hydroxyflavones: total syntheses and absolute configuration assignments of (+)-ponapensin and (+)-elliptifoline.

Authors:  Neil J Lajkiewicz; Stéphane P Roche; Baudouin Gerard; John A Porco
Journal:  J Am Chem Soc       Date:  2012-07-25       Impact factor: 15.419

7.  A photochemical flow reactor for large scale syntheses of aglain and rocaglate natural product analogues.

Authors:  Han Yueh; Qiwen Gao; John A Porco; Aaron B Beeler
Journal:  Bioorg Med Chem       Date:  2017-06-11       Impact factor: 3.641

Review 8.  Rocaglamide, silvestrol and structurally related bioactive compounds from Aglaia species.

Authors:  Li Pan; John L Woodard; David M Lucas; James R Fuchs; A Douglas Kinghorn
Journal:  Nat Prod Rep       Date:  2014-05-02       Impact factor: 13.423

9.  Total Syntheses of the Isomeric Aglain Natural Products Foveoglin A and Perviridisin B: Selective Excited-State Intramolecular Proton-Transfer Photocycloaddition.

Authors:  Wenyu Wang; Anthony Clay; Retheesh Krishnan; Neil J Lajkiewicz; Lauren E Brown; Jayaraman Sivaguru; John A Porco
Journal:  Angew Chem Int Ed Engl       Date:  2017-10-13       Impact factor: 15.336

10.  Amidino-Rocaglates: A Potent Class of eIF4A Inhibitors.

Authors:  Jennifer Chu; Wenhan Zhang; Regina Cencic; William G Devine; Dmitri Beglov; Thomas Henkel; Lauren E Brown; Sandor Vajda; John A Porco; Jerry Pelletier
Journal:  Cell Chem Biol       Date:  2019-09-10       Impact factor: 8.116

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