Literature DB >> 21337520

The effect of conjugating RGD into 3D alginate hydrogels on adipogenic differentiation of human adipose-derived stromal cells.

Sun-Woong Kang1, Byung-Hyun Cha, Honghyun Park, Kwang-Sook Park, Kuen Yong Lee, Soo-Hong Lee.   

Abstract

The effects of RGD peptide conjugation to alginate hydrogel on the adipogenic differentiation of ASCs was investigated. After 3 d of culture, RGD-modified alginate hydrogels significantly stimulated FAK and integrin α1 gene expressions and vinculin expression in ASCs. In addition, RGD-modified alginate hydrogels significantly enhanced the adipogenic differentiation of human ASCs to exhibit higher expression levels of oil red O staining and adipogenic genes compared to those of the control group (unmodified gels). These results suggest potential applications of RGD-modified alginate gels for adipose tissue regeneration.
Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

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Year:  2011        PMID： 21337520     DOI： 10.1002/mabi.201000479

Source DB:  PubMed          Journal:  Macromol Biosci        ISSN： 1616-5187            Impact factor:   4.979


  17 in total

1.  Evaluation of a laminin-alginate biomaterial, adipocytes, and adipocyte-derived stem cells interaction in animal autologous fat grafting model using 7-Tesla magnetic resonance imaging.

Authors:  Yo-Shen Chen; Yu-Sheng Hsueh; Yen-Yu Chen; Cheng-Yu Lo; Hao-Chih Tai; Feng-Huei Lin
Journal:  J Mater Sci Mater Med       Date:  2016-12-20       Impact factor: 3.896

2.  Photocrosslinkable, biodegradable hydrogels with controlled cell adhesivity for prolonged siRNA delivery to hMSCs to enhance their osteogenic differentiation.

Authors:  Minh Khanh Nguyen; Alexandra McMillan; Cong Truc Huynh; Daniel S Schapira; Eben Alsberg
Journal:  J Mater Chem B       Date:  2016-12-14       Impact factor: 6.331

3.  The effect of RGD peptide on 2D and miniaturized 3D culture of HEPM cells, MSCs, and ADSCs with alginate hydrogel.

Authors:  Jenna Dumbleton; Pranay Agarwal; Haishui Huang; Nathaniel Hogrebe; Renzhi Han; Keith J Gooch; Xiaoming He
Journal:  Cell Mol Bioeng       Date:  2016-01-26       Impact factor: 2.321

4.  Photofunctionalization of alginate hydrogels to promote adhesion and proliferation of human mesenchymal stem cells.

Authors:  Oju Jeon; Eben Alsberg
Journal:  Tissue Eng Part A       Date:  2013-02-26       Impact factor: 3.845

5.  Biochemical and physical signal gradients in hydrogels to control stem cell behavior.

Authors:  Oju Jeon; Daniel S Alt; Stephen W Linderman; Eben Alsberg
Journal:  Adv Mater       Date:  2013-08-25       Impact factor: 30.849

Review 6.  Opportunities and challenges in three-dimensional brown adipogenesis of stem cells.

Authors:  Andrea M Unser; Yangzi Tian; Yubing Xie
Journal:  Biotechnol Adv       Date:  2015-07-29       Impact factor: 14.227

7.  Human Periodontal Ligament- and Gingiva-derived Mesenchymal Stem Cells Promote Nerve Regeneration When Encapsulated in Alginate/Hyaluronic Acid 3D Scaffold.

Authors:  Sahar Ansari; Ivana M Diniz; Chider Chen; Patricia Sarrion; Ali Tamayol; Benjamin M Wu; Alireza Moshaverinia
Journal:  Adv Healthc Mater       Date:  2017-10-27       Impact factor: 9.933

Review 8.  Dental and orofacial mesenchymal stem cells in craniofacial regeneration: The prosthodontist's point of view.

Authors:  Sahar Ansari; Jackson T Seagroves; Chider Chen; Kumar Shah; Tara Aghaloo; Benjamin M Wu; Sompop Bencharit; Alireza Moshaverinia
Journal:  J Prosthet Dent       Date:  2017-04-03       Impact factor: 3.426

9.  Dual-stage growth factor release within 3D protein-engineered hydrogel niches promotes adipogenesis.

Authors:  Midori Greenwood-Goodwin; Eric S Teasley; Sarah C Heilshorn
Journal:  Biomater Sci       Date:  2014-11-01       Impact factor: 6.843

10.  Enzymatically crosslinked silk and silk-gelatin hydrogels with tunable gelation kinetics, mechanical properties and bioactivity for cell culture and encapsulation.

Authors:  Onur Hasturk; Kathryn E Jordan; Jaewon Choi; David L Kaplan
Journal:  Biomaterials       Date:  2019-12-23       Impact factor: 12.479
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