OBJECTIVE: To compare the efficacy of oral dydrogesterone with that of micronized vaginal P gel and micronized P capsule for luteal supplementation. DESIGN: Prospective, randomized clinical study. SETTING: Institute of Reproductive Medicine, Kolkata, India. PATIENT(S): A total of 1,373 infertile women undergoing IVF participated. INTERVENTION(S): Micronized P gel, P capsule, and oral dydrogesterone were administered for luteal support and compared. MAIN OUTCOME MEASURE(S): Demographic profile and pregnancy and miscarriage rates. RESULT(S): The overall pregnancy rate and miscarriage rate were comparable among the three groups. CONCLUSION(S): Oral dydrogesterone seems to be a promising drug for luteal support in woman undergoing IVF.
RCT Entities:
OBJECTIVE: To compare the efficacy of oral dydrogesterone with that of micronized vaginal P gel and micronized P capsule for luteal supplementation. DESIGN: Prospective, randomized clinical study. SETTING: Institute of Reproductive Medicine, Kolkata, India. PATIENT(S): A total of 1,373 infertile women undergoing IVF participated. INTERVENTION(S): Micronized P gel, P capsule, and oral dydrogesterone were administered for luteal support and compared. MAIN OUTCOME MEASURE(S): Demographic profile and pregnancy and miscarriage rates. RESULT(S): The overall pregnancy rate and miscarriage rate were comparable among the three groups. CONCLUSION(S): Oral dydrogesterone seems to be a promising drug for luteal support in woman undergoing IVF.
Authors: Michelle van der Linden; Karen Buckingham; Cindy Farquhar; Jan A M Kremer; Mostafa Metwally Journal: Cochrane Database Syst Rev Date: 2015-07-07
Authors: Laura Jeschke; Clarisa Guillermina Santamaria; Nicole Meyer; Ana Claudia Zenclussen; Julia Bartley; Anne Schumacher Journal: Int J Mol Sci Date: 2021-05-20 Impact factor: 5.923
Authors: Valerie L Baker; Christopher A Jones; Kevin Doody; Russell Foulk; Bill Yee; G David Adamson; Barbara Cometti; Gary DeVane; Gary Hubert; Silvia Trevisan; Fred Hoehler; Clarence Jones; Michael Soules Journal: Hum Reprod Date: 2014-08-06 Impact factor: 6.918