Literature DB >> 21329946

Saddle-shaped mitral valve annuloplasty rings improve leaflet coaptation geometry.

Morten O Jensen1, Henrik Jensen, Robert A Levine, Ajit P Yoganathan, Niels Trolle Andersen, Hans Nygaard, J Michael Hasenkam, Sten L Nielsen.   

Abstract

OBJECTIVES: The mitral valve annulus naturally conforms to a saddle shape in systole. This configuration is believed to put the leaflets into a lower-energy equilibrium with the annulus and subvalvular apparatus. Conventional flat annuloplasty rings restrict posterior leaflet motion, which may result in a "monocusp" valve, affecting valvular stress distribution. It is hypothesized that saddle-shaped annuloplasty rings cause less distortion of the physiologic leaflet geometry than do flat rings.
METHODS: Twelve pigs were studied in an acute setting with 3-dimensional echocardiography and sonomicrometry before and after implantation of rigid flat (n = 5) and saddle-shaped (n = 7) annuloplasty rings. The rings were true sized to the annulus with equal anterior-posterior and commissure-commissure circumferential dimensions. The saddle-shaped rings had an annular height to commissural width ratio of 15%.
RESULTS: Saddle-shaped rings maintained both leaflets operational (P < .01). Flat rings made the posterior leaflet immobile and the anterior leaflet aligned flat along the annulus in systole, effectively resulting in monoleaflet function. The average distance from the papillary muscle tips to the posterior annulus decreased by 2.4 ± 0.4 mm after flat ring implantation (P < .01).
CONCLUSIONS: Saddle-shaped annuloplasty rings provide better leaflet coaptation geometry than do flat rings by not hoisting the papillary muscles toward the posterior annulus through the commissural chordae, allowing greater leaflet mobility. This entails a potentially beneficial impact on valvular stress distribution that could affect durability of the repaired valve.
Copyright © 2011 The American Association for Thoracic Surgery. Published by Mosby, Inc. All rights reserved.

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Year:  2011        PMID: 21329946      PMCID: PMC3224846          DOI: 10.1016/j.jtcvs.2011.01.022

Source DB:  PubMed          Journal:  J Thorac Cardiovasc Surg        ISSN: 0022-5223            Impact factor:   5.209


  32 in total

1.  Annular height-to-commissural width ratio of annulolasty rings in vivo.

Authors:  Tomasz A Timek; Julie R Glasson; David T Lai; David Liang; George T Daughters; Neil B Ingels; D Craig Miller
Journal:  Circulation       Date:  2005-08-30       Impact factor: 29.690

2.  Effects of hemodynamic alterations on anterior mitral leaflet curvature during systole.

Authors:  Hiroaki Sakamoto; Landi M Parish; Hirotsugu Hamamoto; Yoshiharu Enomoto; Ahmad Zeeshan; Theodore Plappert; Benjamin M Jackson; Martin G St John-Sutton; Robert C Gorman; Joseph H Gorman
Journal:  J Thorac Cardiovasc Surg       Date:  2006-12       Impact factor: 5.209

3.  A saddle-shaped annulus reduces systolic strain on the central region of the mitral valve anterior leaflet.

Authors:  Jorge H Jimenez; Shasan W Liou; Muralidhar Padala; Zhaoming He; Michael Sacks; Robert C Gorman; Joseph H Gorman; Ajit P Yoganathan
Journal:  J Thorac Cardiovasc Surg       Date:  2007-12       Impact factor: 5.209

4.  What forces act on a flat rigid mitral annuloplasty ring?

Authors:  Morten Ø Jensen; Henrik Jensen; Sten L Nielsen; Morten Smerup; Peter Johansen; Ajit P Yoganathan; Hans Nygaard; J Michael Hasenkam
Journal:  J Heart Valve Dis       Date:  2008-05

5.  Effects of undersized mitral annuloplasty on regional transmural left ventricular wall strains and wall thickening mechanisms.

Authors:  Allen Cheng; Tom C Nguyen; Marcin Malinowski; David Liang; George T Daughters; Neil B Ingels; D Craig Miller
Journal:  Circulation       Date:  2006-07-04       Impact factor: 29.690

6.  Mechanism of recurrent/persistent ischemic/functional mitral regurgitation in the chronic phase after surgical annuloplasty: importance of augmented posterior leaflet tethering.

Authors:  Eiji Kuwahara; Yutaka Otsuji; Yoshifumi Iguro; Tetsuya Ueno; Fang Zhu; Naoko Mizukami; Kayoko Kubota; Kenichi Nakashiki; Toshinori Yuasa; Bo Yu; Takeshi Uemura; Kunitsugu Takasaki; Masaaki Miyata; Shuichi Hamasaki; Akira Kisanuki; Robert A Levine; Ryuzo Sakata; Chuwa Tei
Journal:  Circulation       Date:  2006-07-04       Impact factor: 29.690

7.  Imbalanced chordal force distribution causes acute ischemic mitral regurgitation: mechanistic insights from chordae tendineae force measurements in pigs.

Authors:  Sten Lyager Nielsen; Søren B Hansen; Katrine O Nielsen; Hans Nygaard; Peter K Paulsen; J Michael Hasenkam
Journal:  J Thorac Cardiovasc Surg       Date:  2005-03       Impact factor: 5.209

8.  Durability of mitral valve repair for degenerative disease.

Authors:  A M Gillinov; D M Cosgrove; E H Blackstone; R Diaz; J H Arnold; B W Lytle; N G Smedira; J F Sabik; P M McCarthy; F D Loop
Journal:  J Thorac Cardiovasc Surg       Date:  1998-11       Impact factor: 5.209

9.  The influence of annuloplasty ring geometry on mitral leaflet curvature.

Authors:  Liam P Ryan; Benjamin M Jackson; Hirotsuga Hamamoto; Thomas J Eperjesi; Theodore J Plappert; Martin St John-Sutton; Robert C Gorman; Joseph H Gorman
Journal:  Ann Thorac Surg       Date:  2008-09       Impact factor: 4.330

10.  Saddle-shaped mitral valve annuloplasty rings experience lower forces compared with flat rings.

Authors:  Morten O Jensen; Henrik Jensen; Morten Smerup; Robert A Levine; Ajit P Yoganathan; Hans Nygaard; J Michael Hasenkam; Sten L Nielsen
Journal:  Circulation       Date:  2008-09-30       Impact factor: 29.690

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  28 in total

Review 1.  Mitral valve disease--morphology and mechanisms.

Authors:  Robert A Levine; Albert A Hagége; Daniel P Judge; Muralidhar Padala; Jacob P Dal-Bianco; Elena Aikawa; Jonathan Beaudoin; Joyce Bischoff; Nabila Bouatia-Naji; Patrick Bruneval; Jonathan T Butcher; Alain Carpentier; Miguel Chaput; Adrian H Chester; Catherine Clusel; Francesca N Delling; Harry C Dietz; Christian Dina; Ronen Durst; Leticia Fernandez-Friera; Mark D Handschumacher; Morten O Jensen; Xavier P Jeunemaitre; Hervé Le Marec; Thierry Le Tourneau; Roger R Markwald; Jean Mérot; Emmanuel Messas; David P Milan; Tui Neri; Russell A Norris; David Peal; Maelle Perrocheau; Vincent Probst; Michael Pucéat; Nadia Rosenthal; Jorge Solis; Jean-Jacques Schott; Ehud Schwammenthal; Susan A Slaugenhaupt; Jae-Kwan Song; Magdi H Yacoub
Journal:  Nat Rev Cardiol       Date:  2015-10-20       Impact factor: 32.419

2.  The choice of mitral annuloplastic ring-beyond "surgeon's preference".

Authors:  Song Wan; Alex P W Lee; Chun-Na Jin; Randolph H L Wong; Herman H M Chan; Calvin S H Ng; Innes Y P Wan; Malcolm J Underwood
Journal:  Ann Cardiothorac Surg       Date:  2015-05

Review 3.  Basic mechanisms of mitral regurgitation.

Authors:  Jacob P Dal-Bianco; Jonathan Beaudoin; Mark D Handschumacher; Robert A Levine
Journal:  Can J Cardiol       Date:  2014-07-02       Impact factor: 5.223

4.  Physiological mitral annular dynamics preserved after ring annuloplasty in mid-term period.

Authors:  Masaaki Ryomoto; Masataka Mitsuno; Mitsuhiro Yamamura; Hiroe Tanaka; Naosumi Sekiya; Hisashi Uemura; Ayaka Sato; Daisuke Ueda; Yuji Miyamoto
Journal:  Gen Thorac Cardiovasc Surg       Date:  2017-08-08

5.  Mitral valve geometry in paediatric rheumatic mitral regurgitation.

Authors:  Michael Yeong; Marcus Silbery; Kirsten Finucane; Nigel J Wilson; Thomas L Gentles
Journal:  Pediatr Cardiol       Date:  2015-01-06       Impact factor: 1.655

6.  Measurement of mitral leaflet and annular geometry and stress after repair of posterior leaflet prolapse: virtual repair using a patient-specific finite element simulation.

Authors:  Liang Ge; William G Morrel; Alison Ward; Rakesh Mishra; Zhihong Zhang; Julius M Guccione; Eugene A Grossi; Mark B Ratcliffe
Journal:  Ann Thorac Surg       Date:  2014-03-13       Impact factor: 4.330

7.  A novel 3D-Printed preferential posterior mitral annular dilation device delineates regurgitation onset threshold in an ex vivo heart simulator.

Authors:  Annabel M Imbrie-Moore; Cole C Paullin; Michael J Paulsen; Frederick Grady; Hanjay Wang; Camille E Hironaka; Justin M Farry; Haley J Lucian; Y Joseph Woo
Journal:  Med Eng Phys       Date:  2020-01-31       Impact factor: 2.242

8.  The unsaddled annulus: biomechanical culprit in mitral valve prolapse?

Authors:  Morten O Jensen; Albert A Hagège; Yutaka Otsuji; Robert A Levine
Journal:  Circulation       Date:  2013-02-19       Impact factor: 29.690

9.  Mitral valve mechanics following posterior leaflet patch augmentation.

Authors:  Azadeh Rahmani; Ann Q Rasmussen; Jesper L Honge; Bjorn Ostli; Robert A Levine; Albert Hagège; Hans Nygaard; Sten L Nielsen; Morten O Jensen
Journal:  J Heart Valve Dis       Date:  2013-01

Review 10.  Functional mitral regurgitation: a 30-year unresolved surgical journey from valve replacement to complex valve repairs.

Authors:  Francesco Onorati; Francesco Santini; Rajesh Dandale; Andrea Rossi; Esther Campopiano; Konstantinos Pechlivanidis; Daniele Calzaferri; Aldo Milano; Alessandro Mazzucco; Giuseppe Faggian
Journal:  Heart Fail Rev       Date:  2014-05       Impact factor: 4.214

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