Literature DB >> 18824763

Saddle-shaped mitral valve annuloplasty rings experience lower forces compared with flat rings.

Morten O Jensen1, Henrik Jensen, Morten Smerup, Robert A Levine, Ajit P Yoganathan, Hans Nygaard, J Michael Hasenkam, Sten L Nielsen.   

Abstract

BACKGROUND: New insight into the 3D dynamic behavior of the mitral valve has prompted a reevaluation of annuloplasty ring designs. Force balance analysis indicates correlation between annulus forces and stresses in leaflets and chords. Improving this stress distribution can intuitively enhance the durability of mitral valve repair. We tested the hypothesis that saddle-shaped annuloplasty rings have superior uniform systolic force distribution compared with a nonuniform force distribution in flat annuloplasty rings. METHODS AND
RESULTS: Sixteen 80-kg pigs had a flat (n=8) or saddle-shaped (n=8) mitral annuloplasty ring implanted. Mitral annulus 3D dynamic geometry was obtained with sonomicrometry before ring insertion. Strain gauges mounted on dedicated D-shaped rigid flat and saddle-shaped annuloplasty rings provided the intraoperative force distribution perpendicular to the annular plane. Average systolic annular height to commissural width ratio before ring implantation was 14.0%+/-1.6%. After flat and saddle shaped ring implantation, the annulus was fixed in the diastolic (9.0%+/-1.0%) and systolic (14.3%+/-1.3%) configuration, respectively (P<0.01). Force accumulation was seen from the anterior (0.72N+/-0.14N) and commissural annular segments (average 1.38N+/-0.27N) of the flat rings. In these segments, the difference between the 2 types of rings was statistically significant (P<0.05). The saddle-shaped annuloplasty rings did not experience forces statistically significantly larger than zero in any annular segments.
CONCLUSIONS: Saddle-shaped annuloplasty rings provide superior uniform annular force distribution compared to flat rings and appear to represent a configuration that minimizes out-of-plane forces that could potentially be transmitted to leaflets and chords. This may have important implications for annuloplasty ring selections.

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Year:  2008        PMID: 18824763     DOI: 10.1161/CIRCULATIONAHA.107.746776

Source DB:  PubMed          Journal:  Circulation        ISSN: 0009-7322            Impact factor:   29.690


  38 in total

1.  Role of Mitral Annulus Diastolic Geometry on Intraventricular Filling Dynamics.

Authors:  Ikechukwu U Okafor; Arvind Santhanakrishnan; Vrishank S Raghav; Ajit P Yoganathan
Journal:  J Biomech Eng       Date:  2015-12       Impact factor: 2.097

Review 2.  Mitral valve disease--morphology and mechanisms.

Authors:  Robert A Levine; Albert A Hagége; Daniel P Judge; Muralidhar Padala; Jacob P Dal-Bianco; Elena Aikawa; Jonathan Beaudoin; Joyce Bischoff; Nabila Bouatia-Naji; Patrick Bruneval; Jonathan T Butcher; Alain Carpentier; Miguel Chaput; Adrian H Chester; Catherine Clusel; Francesca N Delling; Harry C Dietz; Christian Dina; Ronen Durst; Leticia Fernandez-Friera; Mark D Handschumacher; Morten O Jensen; Xavier P Jeunemaitre; Hervé Le Marec; Thierry Le Tourneau; Roger R Markwald; Jean Mérot; Emmanuel Messas; David P Milan; Tui Neri; Russell A Norris; David Peal; Maelle Perrocheau; Vincent Probst; Michael Pucéat; Nadia Rosenthal; Jorge Solis; Jean-Jacques Schott; Ehud Schwammenthal; Susan A Slaugenhaupt; Jae-Kwan Song; Magdi H Yacoub
Journal:  Nat Rev Cardiol       Date:  2015-10-20       Impact factor: 32.419

3.  The choice of mitral annuloplastic ring-beyond "surgeon's preference".

Authors:  Song Wan; Alex P W Lee; Chun-Na Jin; Randolph H L Wong; Herman H M Chan; Calvin S H Ng; Innes Y P Wan; Malcolm J Underwood
Journal:  Ann Cardiothorac Surg       Date:  2015-05

4.  How do annuloplasty rings affect mitral leaflet dynamic motion?

Authors:  Wolfgang Bothe; John-Peder Escobar Kvitting; Julia C Swanson; Serdar Göktepe; Kathy N Vo; Neil B Ingels; D Craig Miller
Journal:  Eur J Cardiothorac Surg       Date:  2010-03-23       Impact factor: 4.191

5.  Physiological mitral annular dynamics preserved after ring annuloplasty in mid-term period.

Authors:  Masaaki Ryomoto; Masataka Mitsuno; Mitsuhiro Yamamura; Hiroe Tanaka; Naosumi Sekiya; Hisashi Uemura; Ayaka Sato; Daisuke Ueda; Yuji Miyamoto
Journal:  Gen Thorac Cardiovasc Surg       Date:  2017-08-08

6.  Implantation of personalized, biocompatible mitral annuloplasty rings: feasibility study in an animal model.

Authors:  Simon H Sündermann; Michael Gessat; Nikola Cesarovic; Thomas Frauenfelder; Patric Biaggi; Dominique Bettex; Volkmar Falk; Stephan Jacobs
Journal:  Interact Cardiovasc Thorac Surg       Date:  2013-01-03

7.  Finite Element Analysis of Patient-Specific Mitral Valve with Mitral Regurgitation.

Authors:  Thuy Pham; Fanwei Kong; Caitlin Martin; Qian Wang; Charles Primiano; Raymond McKay; John Elefteriades; Wei Sun
Journal:  Cardiovasc Eng Technol       Date:  2017-01-09       Impact factor: 2.495

8.  Statistical assessment of normal mitral annular geometry using automated three-dimensional echocardiographic analysis.

Authors:  Alison M Pouch; Mathieu Vergnat; Jeremy R McGarvey; Giovanni Ferrari; Benjamin M Jackson; Chandra M Sehgal; Paul A Yushkevich; Robert C Gorman; Joseph H Gorman
Journal:  Ann Thorac Surg       Date:  2013-10-01       Impact factor: 4.330

9.  The unsaddled annulus: biomechanical culprit in mitral valve prolapse?

Authors:  Morten O Jensen; Albert A Hagège; Yutaka Otsuji; Robert A Levine
Journal:  Circulation       Date:  2013-02-19       Impact factor: 29.690

10.  The effect of surgical and transcatheter aortic valve replacement on mitral annular anatomy.

Authors:  Mathieu Vergnat; Melissa M Levack; Benjamin M Jackson; Joseph E Bavaria; Howard C Herrmann; Albert T Cheung; Stuart J Weiss; Joseph H Gorman; Robert C Gorman
Journal:  Ann Thorac Surg       Date:  2012-12-13       Impact factor: 4.330

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