Literature DB >> 21323369

A catalytic route to ampakines and their derivatives.

Michael Mulzer1, Geoffrey W Coates.   

Abstract

A catalytic domino reaction that efficiently provides access to an important class of heterocycles, the ampakines, is reported. Our approach is based on the cobalt-catalyzed hydroformylation of dihydrooxazines and allows for the facile synthesis of the pharmaceutically interesting compound CX-614 and related substances.

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Year:  2011        PMID: 21323369     DOI: 10.1021/ol200111a

Source DB:  PubMed          Journal:  Org Lett        ISSN: 1523-7052            Impact factor:   6.005


  3 in total

1.  Crystal structure of 3-bromo-2-hy-droxy-benzo-nitrile.

Authors:  Sean R Dickinson; Peter Müller; Joseph M Tanski
Journal:  Acta Crystallogr E Crystallogr Commun       Date:  2015-06-27

2.  ZnCl2-promoted domino reaction of 2-hydroxybenzonitriles with ketones for synthesis of 1,3-benzoxazin-4-ones.

Authors:  Ziqi Su; Hongxin Chai; Juan Xu; Jiarong Li
Journal:  RSC Adv       Date:  2021-09-06       Impact factor: 4.036

3.  Facile cleavage of C-C bond: conversion of pyrane derivative to 1,3-oxazin derivative.

Authors:  Zhilan Lin; Xueli Zhang; Xinkui You; Yuan Gao
Journal:  Tetrahedron       Date:  2012-05-30       Impact factor: 2.457

  3 in total

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