Literature DB >> 21321076

Reductionistic and holistic science.

Ferric C Fang, Arturo Casadevall.   

Abstract

A reductionistic approach to science, epitomized by molecular biology, is often contrasted with the holistic approach of systems biology. However, molecular biology and systems biology are actually interdependent and complementary ways in which to study and make sense of complex phenomena.

Mesh：

Year:  2011        PMID： 21321076      PMCID： PMC3067528          DOI： 10.1128/IAI.01343-10

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  38 in total

1.  Integrating high-throughput and computational data elucidates bacterial networks.

Authors:  Markus W Covert; Eric M Knight; Jennifer L Reed; Markus J Herrgard; Bernhard O Palsson
Journal:  Nature       Date:  2004-05-06       Impact factor: 49.962

2.  Systems biology and new technologies enable predictive and preventative medicine.

Authors:  Leroy Hood; James R Heath; Michael E Phelps; Biaoyang Lin
Journal:  Science       Date:  2004-10-22       Impact factor: 47.728

3.  Ins and outs of systems biology vis-à-vis molecular biology: continuation or clear cut?

Authors:  Philippe De Backer; Danny De Waele; Linda Van Speybroeck
Journal:  Acta Biotheor       Date:  2009-10-24       Impact factor: 1.774

4.  STUDIES ON THE CHEMICAL NATURE OF THE SUBSTANCE INDUCING TRANSFORMATION OF PNEUMOCOCCAL TYPES : INDUCTION OF TRANSFORMATION BY A DESOXYRIBONUCLEIC ACID FRACTION ISOLATED FROM PNEUMOCOCCUS TYPE III.

Authors:  O T Avery; C M Macleod; M McCarty
Journal:  J Exp Med       Date:  1944-02-01       Impact factor: 14.307

5.  A single genetic locus encoded by Yersinia pseudotuberculosis permits invasion of cultured animal cells by Escherichia coli K-12.

Authors:  R R Isberg; S Falkow
Journal:  Nature       Date:  1985 Sep 19-25       Impact factor: 49.962

6.  Transcriptome of swarming Proteus mirabilis.

Authors:  Melanie M Pearson; David A Rasko; Sara N Smith; Harry L T Mobley
Journal:  Infect Immun       Date:  2010-04-05       Impact factor: 3.441

7.  Genetic control of susceptibility to Salmonella typhimurium in mice: role of the LPS gene.

Authors:  A D O'Brien; D L Rosenstreich; I Scher; G H Campbell; R P MacDermott; S B Formal
Journal:  J Immunol       Date:  1980-01       Impact factor: 5.422

8.  Genome-wide RNAi screen identifies human host factors crucial for influenza virus replication.

Authors:  Alexander Karlas; Nikolaus Machuy; Yujin Shin; Klaus-Peter Pleissner; Anita Artarini; Dagmar Heuer; Daniel Becker; Hany Khalil; Lesley A Ogilvie; Simone Hess; André P Mäurer; Elke Müller; Thorsten Wolff; Thomas Rudel; Thomas F Meyer
Journal:  Nature       Date:  2010-01-17       Impact factor: 49.962

9.  Mutants of Salmonella typhimurium that cannot survive within the macrophage are avirulent.

Authors:  P I Fields; R V Swanson; C G Haidaris; F Heffron
Journal:  Proc Natl Acad Sci U S A       Date:  1986-07       Impact factor: 11.205

Review 10.  The nature of systems biology.

Authors:  Frank J Bruggeman; Hans V Westerhoff
Journal:  Trends Microbiol       Date:  2006-11-20       Impact factor: 17.079
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  24 in total

1.  Molecular studies neglect apparently gram-negative populations in the human gut microbiota.

Authors:  Perrine Hugon; Jean-Christophe Lagier; Catherine Robert; Catherine Lepolard; Laurent Papazian; Didier Musso; Bernard Vialettes; Didier Raoult
Journal:  J Clin Microbiol       Date:  2013-07-24       Impact factor: 5.948

2.  Retracted science and the retraction index.

Authors:  Ferric C Fang; Arturo Casadevall
Journal:  Infect Immun       Date:  2011-08-08       Impact factor: 3.441

3.  47 Years of IAI: a Glance in the Mirror and the Road Ahead.

Authors:  Ferric C Fang
Journal:  Infect Immun       Date:  2017-06-20       Impact factor: 3.441

Review 4.  Online tools for bioinformatics analyses in nutrition sciences.

Authors:  Sridhar A Malkaram; Yousef I Hassan; Janos Zempleni
Journal:  Adv Nutr       Date:  2012-09-01       Impact factor: 8.701

Review 5.  From Reductionism to Holism: Toward a More Complete View of Development Through Genome Engineering.

Authors:  Rebecca K Delker; Richard S Mann
Journal:  Adv Exp Med Biol       Date:  2017       Impact factor: 2.622

6.  What is One Health?

Authors:  Michele Anholt; Herman Barkema
Journal:  Can Vet J       Date:  2021-06       Impact factor: 1.008

7.  An Object-Oriented Regression for Building Disease Predictive Models with Multiallelic HLA Genes.

Authors:  Lue Ping Zhao; Hamid Bolouri; Michael Zhao; Daniel E Geraghty; Åke Lernmark
Journal:  Genet Epidemiol       Date:  2016-05       Impact factor: 2.135

Review 8.  Multitissue Multiomics Systems Biology to Dissect Complex Diseases.

Authors:  Xia Yang
Journal:  Trends Mol Med       Date:  2020-05-18       Impact factor: 11.951

9.  From Microbial Dynamics to Functionality in the Rhizosphere: A Systematic Review of the Opportunities With Synthetic Microbial Communities.

Authors:  Olga Marín; Bernardo González; María Josefina Poupin
Journal:  Front Plant Sci       Date:  2021-06-03       Impact factor: 5.753

10.  Systems biology, bioinformatics, and biomarkers in neuropsychiatry.

Authors:  Ali Alawieh; Fadi A Zaraket; Jian-Liang Li; Stefania Mondello; Amaly Nokkari; Mahdi Razafsha; Bilal Fadlallah; Rose-Mary Boustany; Firas H Kobeissy
Journal:  Front Neurosci       Date:  2012-12-24       Impact factor: 4.677
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