Literature DB >> 21318127

Histone modifications and chromatin organization in prostate cancer.

Zhong Chen1, Liguo Wang, Qianben Wang, Wei Li.   

Abstract

Epigenetic mechanisms, including histone modifications, nucleosomal remodeling and chromosomal looping, contribute to the onset and progression of prostate cancer. Recent technical advances significantly increase our understanding of the genome-wide epigenetic regulation of gene expression in prostate cancer. Aberrant genomic distribution and global level of histone modifications, nucleosome repositioning at the gene promoter and enhancer regions, as well as androgen receptor-mediated chromosomal looping may lead to the silencing of tumor suppressor genes and the activation of proto-oncogenes. In addition, androgen receptor-induced chromosomal looping facilitates recurrent gene fusion in prostate cancer. Studies in epigenetic regulation have translational implications in the identification of new biomarkers and the development of new therapies in prostate cancer.

Entities:  

Keywords:  CHIA-PET; ChIP-seq; Hi-C; bioinformatics; chromatin organization; epigenome; histone modification; next-generation sequencing; prostate cancer

Mesh：

Substances：

Year:  2010        PMID： 21318127      PMCID： PMC3035388          DOI： 10.2217/epi.10.31

Source DB:  PubMed          Journal:  Epigenomics        ISSN： 1750-192X            Impact factor:   4.778


  89 in total

1.  Chromatin, transcript elongation and alternative splicing.

Authors:  Alberto R Kornblihtt
Journal:  Nat Struct Mol Biol       Date:  2006-01       Impact factor: 15.369

Review 2.  Epigenetics of long-range chromatin interactions.

Authors:  Jian Qun Ling; Andrew R Hoffman
Journal:  Pediatr Res       Date:  2007-05       Impact factor: 3.756

3.  Mapping short DNA sequencing reads and calling variants using mapping quality scores.

Authors:  Heng Li; Jue Ruan; Richard Durbin
Journal:  Genome Res       Date:  2008-08-19       Impact factor: 9.043

4.  Distinct and predictive chromatin signatures of transcriptional promoters and enhancers in the human genome.

Authors:  Nathaniel D Heintzman; Rhona K Stuart; Gary Hon; Yutao Fu; Christina W Ching; R David Hawkins; Leah O Barrera; Sara Van Calcar; Chunxu Qu; Keith A Ching; Wei Wang; Zhiping Weng; Roland D Green; Gregory E Crawford; Bing Ren
Journal:  Nat Genet       Date:  2007-02-04       Impact factor: 38.330

5.  A global view of gene activity and alternative splicing by deep sequencing of the human transcriptome.

Authors:  Marc Sultan; Marcel H Schulz; Hugues Richard; Alon Magen; Andreas Klingenhoff; Matthias Scherf; Martin Seifert; Tatjana Borodina; Aleksey Soldatov; Dmitri Parkhomchuk; Dominic Schmidt; Sean O'Keeffe; Stefan Haas; Martin Vingron; Hans Lehrach; Marie-Laure Yaspo
Journal:  Science       Date:  2008-07-03       Impact factor: 47.728

Review 6.  Chromosome crosstalk in three dimensions.

Authors:  Anita Göndör; Rolf Ohlsson
Journal:  Nature       Date:  2009-09-10       Impact factor: 49.962

7.  Global mapping of H3K4me3 and H3K27me3 reveals specificity and plasticity in lineage fate determination of differentiating CD4+ T cells.

Authors:  Gang Wei; Lai Wei; Jinfang Zhu; Chongzhi Zang; Jane Hu-Li; Zhengju Yao; Kairong Cui; Yuka Kanno; Tae-Young Roh; Wendy T Watford; Dustin E Schones; Weiqun Peng; Hong-Wei Sun; William E Paul; John J O'Shea; Keji Zhao
Journal:  Immunity       Date:  2009-01-16       Impact factor: 31.745

8.  Androgen receptor regulates a distinct transcription program in androgen-independent prostate cancer.

Authors:  Qianben Wang; Wei Li; Yong Zhang; Xin Yuan; Kexin Xu; Jindan Yu; Zhong Chen; Rameen Beroukhim; Hongyun Wang; Mathieu Lupien; Tao Wu; Meredith M Regan; Clifford A Meyer; Jason S Carroll; Arjun Kumar Manrai; Olli A Jänne; Steven P Balk; Rohit Mehra; Bo Han; Arul M Chinnaiyan; Mark A Rubin; Lawrence True; Michelangelo Fiorentino; Christopher Fiore; Massimo Loda; Philip W Kantoff; X Shirley Liu; Myles Brown
Journal:  Cell       Date:  2009-07-23       Impact factor: 41.582

9.  Global levels of histone modifications predict prognosis in different cancers.

Authors:  David B Seligson; Steve Horvath; Matthew A McBrian; Vei Mah; Hong Yu; Sheila Tze; Qun Wang; David Chia; Lee Goodglick; Siavash K Kurdistani
Journal:  Am J Pathol       Date:  2009-04-06       Impact factor: 4.307

10.  A sequence motif within chromatin entry sites directs MSL establishment on the Drosophila X chromosome.

Authors:  Artyom A Alekseyenko; Shouyong Peng; Erica Larschan; Andrey A Gorchakov; Ok-Kyung Lee; Peter Kharchenko; Sean D McGrath; Charlotte I Wang; Elaine R Mardis; Peter J Park; Mitzi I Kuroda
Journal:  Cell       Date:  2008-08-22       Impact factor: 41.582
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  31 in total

Review 1.  Androgen receptor-driven chromatin looping in prostate cancer.

Authors:  Dayong Wu; Chunpeng Zhang; Yanping Shen; Kenneth P Nephew; Qianben Wang
Journal:  Trends Endocrinol Metab       Date:  2011-08-31       Impact factor: 12.015

2.  MiR-424 functions as a tumor suppressor in glioma cells and is down-regulated by DNA methylation.

Authors:  Chen Jin; Minhong Li; Yian Ouyang; Zhigang Tan; Yugang Jiang
Journal:  J Neurooncol       Date:  2017-05-15       Impact factor: 4.130

3.  Identification of a new liver-specific c-type mRNA transcriptional variant for mouse ST3GAL5 (GM3/GM4 synthase).

Authors:  Fumi Shishido; Satoshi Uemura; Takahiro Nitta; Jin-Ichi Inokuchi
Journal:  Glycoconj J       Date:  2017-08-14       Impact factor: 2.916

Review 4.  Impact of Epigenetic Dietary Components on Cancer through Histone Modifications.

Authors:  Yifeng Gao; Trygve O Tollefsbol
Journal:  Curr Med Chem       Date:  2015       Impact factor: 4.530

5.  Agonist and antagonist switch DNA motifs recognized by human androgen receptor in prostate cancer.

Authors:  Zhong Chen; Xun Lan; Jennifer M Thomas-Ahner; Dayong Wu; Xiangtao Liu; Zhenqing Ye; Liguo Wang; Benjamin Sunkel; Cassandra Grenade; Junsheng Chen; Debra L Zynger; Pearlly S Yan; Jiaoti Huang; Kenneth P Nephew; Tim H-M Huang; Shili Lin; Steven K Clinton; Wei Li; Victor X Jin; Qianben Wang
Journal:  EMBO J       Date:  2014-12-22       Impact factor: 11.598

Review 6.  Prostate cancer epigenome.

Authors:  Swathi Chinaranagari; Pankaj Sharma; Nathan J Bowen; Jaideep Chaudhary
Journal:  Methods Mol Biol       Date:  2015

7.  Epidaurus: aggregation and integration analysis of prostate cancer epigenome.

Authors:  Liguo Wang; Haojie Huang; Gregory Dougherty; Yu Zhao; Asif Hossain; Jean-Pierre A Kocher
Journal:  Nucleic Acids Res       Date:  2014-11-05       Impact factor: 16.971

8.  Scaffold attachment factor B1 regulates the androgen receptor in concert with the growth inhibitory kinase MST1 and the methyltransferase EZH2.

Authors:  N K Mukhopadhyay; J Kim; S You; M Morello; M H Hager; W-C Huang; A Ramachandran; J Yang; B Cinar; M A Rubin; R M Adam; S Oesterreich; D Di Vizio; M R Freeman
Journal:  Oncogene       Date:  2013-07-29       Impact factor: 9.867

Review 9.  Combining genomic and proteomic approaches for epigenetics research.

Authors:  Yumiao Han; Benjamin A Garcia
Journal:  Epigenomics       Date:  2013-08       Impact factor: 4.778

10.  The triterpenoid corosolic acid blocks transformation and epigenetically reactivates Nrf2 in TRAMP-C1 prostate cells.

Authors:  Jie Yang; Renyi Wu; Wenji Li; Linbo Gao; Yuqing Yang; Ping Li; Ah-Ng Kong
Journal:  Mol Carcinog       Date:  2018-01-11       Impact factor: 4.784
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