Literature DB >> 21312302

Silicon-based chemistry: an original and efficient one-step approach to [18F]-nucleosides and [18F]-oligonucleotides for PET imaging.

Jürgen Schulz1, Delphine Vimont, Thomas Bordenave, Damien James, Jean-Marc Escudier, Michèle Allard, Magali Szlosek-Pinaud, Eric Fouquet.   

Abstract

Take it eaSi! Nucleosides, dinucleotides, and one oligonucleotide, all modified by click chemistry, have for the first time been directly and very efficiently labeled with (18)F by using a silicon-based, one-step approach that opens the way for the development of a new class of positron emission tomography (PET) tracers (see graphic).
Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

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Year:  2011        PMID： 21312302     DOI： 10.1002/chem.201003234

Source DB:  PubMed          Journal:  Chemistry        ISSN： 0947-6539            Impact factor:   5.236


  9 in total

1.  Crown Ether Nucleophilic Catalysts (CENCs): Agents for Enhanced Silicon Radiofluorination.

Authors:  Susovan Jana; Mohammed H Al-Huniti; Bo Yeun Yang; Shuiyu Lu; Victor W Pike; Salvatore D Lepore
Journal:  J Org Chem       Date:  2017-02-20       Impact factor: 4.354

2.  Synthesis and 18F-radiolabeling of thymidine AMBF3 conjugates.

Authors:  Antonio A W L Wong; Jerome Lozada; Mathieu L Lepage; Chengcheng Zhang; Helen Merkens; Jutta Zeisler; Kuo-Shyan Lin; François Bénard; David M Perrin
Journal:  RSC Med Chem       Date:  2020-04-23

3.  Enhanced Nucleophilic Fluorination and Radiofluorination of Organosilanes Appended with Potassium-Chelating Leaving Groups.

Authors:  Mohammed H Al-Huniti; Shuiyu Lu; Victor W Pike; Salvatore D Lepore
Journal:  J Fluor Chem       Date:  2014-02-01       Impact factor: 2.050

4.  The 4-N-acyl and 4-N-alkyl gemcitabine analogues with silicon-fluoride-acceptor: Application to 18F-Radiolabeling.

Authors:  Cesar Gonzalez; Andersson Sanchez; Jeffrey Collins; Ksenia Lisova; Jason T Lee; R Michael van Dam; M Alejandro Barbieri; Cheppail Ramachandran; Stanislaw F Wnuk
Journal:  Eur J Med Chem       Date:  2018-02-12       Impact factor: 6.514

Review 5.  ¹⁸F-labeled silicon-based fluoride acceptors: potential opportunities for novel positron emitting radiopharmaceuticals.

Authors:  Vadim Bernard-Gauthier; Carmen Wängler; Esther Schirrmacher; Alexey Kostikov; Klaus Jurkschat; Bjoern Wängler; Ralf Schirrmacher
Journal:  Biomed Res Int       Date:  2014-07-24       Impact factor: 3.411

Review 6.  Nucleic Acid Aptamers: Emerging Applications in Medical Imaging, Nanotechnology, Neurosciences, and Drug Delivery.

Authors:  Pascal Röthlisberger; Cécile Gasse; Marcel Hollenstein
Journal:  Int J Mol Sci       Date:  2017-11-16       Impact factor: 5.923

7.  Radiosynthesis and evaluation of an 18F-labeled silicon containing exendin-4 peptide as a PET probe for imaging insulinoma.

Authors:  Lukas O Dialer; Andreas Jodal; Roger Schibli; Simon M Ametamey; Martin Béhé
Journal:  EJNMMI Radiopharm Chem       Date:  2018-01-02

8.  t-Bu2SiF-derivatized D2-receptor ligands: the first SiFA-containing small molecule radiotracers for target-specific PET-imaging.

Authors:  Ljuba Iovkova-Berends; Carmen Wängler; Thomas Zöller; Georg Höfner; Klaus Theodor Wanner; Christian Rensch; Peter Bartenstein; Alexey Kostikov; Ralf Schirrmacher; Klaus Jurkschat; Björn Wängler
Journal:  Molecules       Date:  2011-09-02       Impact factor: 4.411

Review 9.  Convertible and Constrained Nucleotides: The 2'-Deoxyribose 5'-C-Functionalization Approach, a French Touch.

Authors:  Crystalle Chardet; Corinne Payrastre; Béatrice Gerland; Jean-Marc Escudier
Journal:  Molecules       Date:  2021-09-30       Impact factor: 4.411
  9 in total

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