Literature DB >> 21306978

Workplace exposures and male infertility - a case-control study.

Mohamed El-Helaly1, Nabil Awadalla, Moheb Mansour, Yousef El-Biomy.   

Abstract

OBJECTIVES: This study examined the association between male infertility and certain occupational exposures.
MATERIAL AND METHODS: A case-control study was carried out from January 2008 to February 2009; on 255 infertile men and 267 fertile men controls. Occupational exposure to certain chemical, physical and psychological workplace hazards was assessed by self-report questionnaire. General and andrological examination was conducted for all participants, however, semen analysis was done only for the infertile men cases, because the fertile men controls refused to give semen samples.
RESULTS: After adjustment of confounders, the results revealed that the following workplace exposure factors significantly increased the risk of male infertility: solvents and painting materials (OR: 3.88, 95% CI: 1.50-10.03), lead (OR: 5.43, 95% CI: 1.28-23.13), VDTs and computers (OR: 8.01, 95% CI: 4.03-15.87), shift work (OR: 3.60, 95% CI: 1.12-11.57) and work-related stress (fairly present: OR: 3.11, 95% CI: 1.85-5.24; often present: OR: 3.76, 95% CI: 1.96-7.52).
CONCLUSION: In spite of the limitations of this study, it supports other studies that raise the attention to minimize the exposure to the workplace hazards that may affect the fertility of male workers.

Entities:  

Mesh:

Year:  2010        PMID: 21306978     DOI: 10.2478/v10001-010-0039-y

Source DB:  PubMed          Journal:  Int J Occup Med Environ Health        ISSN: 1232-1087            Impact factor:   1.843


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