| Literature DB >> 21302076 |
S J Black1, J W Goding, G A Gutman, L A Herzenberg, M R Loken, B A Osborne, W van der Loo, N L Warner.
Abstract
Murine antisera raised against allogeneic lymphoid cells often contain antibodies to IgM allotypes. Rarely, allotypic antibodies to IgM have been found after immunization withB. pertussis anti-B. pertussis conjugates. Using both types of antibodies, we have defined a new constant-region locus for both secreted and membrane-bound μ chains. This locus,Ig-6, is closely linked to the previously described H-chain constant-region loci (Ig-1 throughIg-5) and is subject to allelic exclusion. We have identified three alleles and four antigenic specificities ofIg-6.Entities:
Year: 1978 PMID: 21302076 DOI: 10.1007/BF01844009
Source DB: PubMed Journal: Immunogenetics ISSN: 0093-7711 Impact factor: 2.846