Literature DB >> 21296514

Comparison of three different injection methods for arterial phase of Gd-EOB-DTPA enhanced MR imaging of the liver.

Tsutomu Tamada1, Katsuyoshi Ito, Koji Yoshida, Akihiko Kanki, Atsushi Higaki, Daigo Tanimoto, Hiroki Higashi.   

Abstract

OBJECTIVE: To compare three different injection methods for optimizing hepatic arterial phase of gadolinium ethoxybenzyl diethylenetriaminepentaacetic acid (Gd-EOB-DTPA) enhanced MR imaging.
METHODS: Arterial phase images were obtained after the injection of contrast agent at a rate of 3 mL/s with diluted Gd-EOB-DTPA (dilution method) in 27 patients, 3 mL/s with undiluted Gd-EOB-DTPA (3 mL method) in 26 patients and 1 mL/s with undiluted Gd-EOB-DTPA (1 mL method) in 28 patients. In the quantitative evaluation, signal-to-phantom ratios (SPR) of the liver parenchyma, pancreas, renal cortex, portal vein and aorta were evaluated. In the qualitative evaluation, the seven items for image quality of hepatic arterial phase were assessed, and the total score of all items in each subject was calculated.
RESULTS: The score of enhancement of abdominal aorta and total score of seven items in 1 mL method were significantly higher than those in 3 mL method. The SPR of the liver parenchyma in 3 mL method was significantly higher than that in 1 mL method, suggesting substantial hepatic inflow from portal venous return.
CONCLUSION: For the optimal arterial phase imaging, injection rate of 1 mL/s with undiluted Gd-EOB-DTPA is convenient and preferable, compared with other two methods, based on our qualitative analysis.
Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.

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Year:  2011        PMID: 21296514     DOI: 10.1016/j.ejrad.2010.12.082

Source DB:  PubMed          Journal:  Eur J Radiol        ISSN: 0720-048X            Impact factor:   3.528


  15 in total

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8.  Predictive factors of truncation artifacts in the arterial phase of Gd-EOB-DTPA-enhanced MRI: a nationwide multicenter study.

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Review 10.  Liver-specific agents for contrast-enhanced MRI: role in oncological imaging.

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