STUDY OBJECTIVE: To evaluate retrospectively serum albumin concentrations as well as morbidity and mortality of abdominal surgical patients who--if hypoalbuminemic--did not receive human albumin solutions versus those who did receive such solutions. DESIGN: Retrospective observational study. SETTING: Academic community hospital. MEASUREMENTS: The records of 76 consecutive patients who had undergone elective abdominal surgery were reviewed. Preoperative and postoperative serum albumin concentrations up to the seventh day after surgery were recorded. Morbidity and mortality were followed until the time of discharge from the hospital. RESULTS: 38 patients who received albumin replacement if they were hypoalbuminemic versus 38 patients who did not receive albumin replacement showed no significant difference in cumulative (P < 0.52) or individual postoperative complications (infections P < 0.35, cardiovascular complications P < 1.0, organ failure P < 0.67, thromboembolic incidents P < 0.26), and mortality (P < 0.47). CONCLUSIONS: Postoperative serum albumin concentration had no correlation with postoperative morbidity. There is no justification for perioperative albumin replacement in abdominal cancer surgical patients.
STUDY OBJECTIVE: To evaluate retrospectively serum albumin concentrations as well as morbidity and mortality of abdominal surgical patients who--if hypoalbuminemic--did not receive human albumin solutions versus those who did receive such solutions. DESIGN: Retrospective observational study. SETTING: Academic community hospital. MEASUREMENTS: The records of 76 consecutive patients who had undergone elective abdominal surgery were reviewed. Preoperative and postoperative serum albumin concentrations up to the seventh day after surgery were recorded. Morbidity and mortality were followed until the time of discharge from the hospital. RESULTS: 38 patients who received albumin replacement if they were hypoalbuminemic versus 38 patients who did not receive albumin replacement showed no significant difference in cumulative (P < 0.52) or individual postoperative complications (infections P < 0.35, cardiovascular complications P < 1.0, organ failure P < 0.67, thromboembolic incidents P < 0.26), and mortality (P < 0.47). CONCLUSIONS: Postoperative serum albumin concentration had no correlation with postoperative morbidity. There is no justification for perioperative albumin replacement in abdominal cancer surgical patients.
Authors: Gaëtan-Romain Joliat; Arnaud Schoor; Markus Schäfer; Nicolas Demartines; Martin Hübner; Ismail Labgaa Journal: Perioper Med (Lond) Date: 2022-02-15
Authors: Heejoon Jeong; Jie Ae Kim; Mikyung Yang; Hyun Joo Ahn; JinSeok Heo; In Woong Han; Sang Hyun Shin; Nam Young Lee; Woo Jin Kim Journal: J Clin Med Date: 2022-01-26 Impact factor: 4.241
Authors: Stefan J Schaller; Kristina Fuest; Bernhard Ulm; Sebastian Schmid; Catherina Bubb; Rüdiger von Eisenhart-Rothe; Helmut Friess; Chlodwig Kirchhoff; Thomas Stadlbauer; Peter Luppa; Manfred Blobner; Bettina Jungwirth Journal: Trials Date: 2020-08-18 Impact factor: 2.279