Literature DB >> 21293311

Epigenetic impacts on neurodevelopment: pathophysiological mechanisms and genetic modes of action.

Farah R Zahir1, Carolyn J Brown.   

Abstract

Disruptions of genes that are involved in epigenetic functions are known to be causative for several mental retardation/intellectual disability (MR/ID) syndromes. Recent work has highlighted genes with epigenetic functions as being implicated in autism spectrum disorders (ASDs) and schizophrenia (SCZ). The gene-environment interaction is an important factor of pathogenicity for these complex disorders. Epigenetic modifications offer a mechanism by which we can explain how the environment interacts with, and is able to dynamically regulate, the genome. This review aims to provide an overview of the role of epigenetic deregulation in the etiopathology for neurodevelopment disease.

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Year:  2011        PMID： 21293311     DOI： 10.1203/PDR.0b013e318213565e

Source DB:  PubMed          Journal:  Pediatr Res        ISSN： 0031-3998            Impact factor:   3.756


  17 in total

Review 1.  Epigenetics: What does it mean for paediatric practice?

Authors:  Judith G Hall
Journal:  Paediatr Child Health       Date:  2014-01       Impact factor: 2.253

Review 2.  Genetics of schizophrenia from a clinicial perspective.

Authors:  Prachi Kukshal; B K Thelma; Vishwajit L Nimgaonkar; Smita N Deshpande
Journal:  Int Rev Psychiatry       Date:  2012-10

Review 3.  Epigenetic factors and autism spectrum disorders.

Authors:  Bess M Flashner; Mark E Russo; Jenine E Boileau; Derek W Leong; G Ian Gallicano
Journal:  Neuromolecular Med       Date:  2013-03-07       Impact factor: 3.843

4.  Life before birth: are the dice tossed for the rest of our lives?

Authors:  Nanda N J Rommelse
Journal:  Eur Child Adolesc Psychiatry       Date:  2012-04       Impact factor: 4.785

5.  Social brain development in williams syndrome: the current status and directions for future research.

Authors:  Brian W Haas; Allan L Reiss
Journal:  Front Psychol       Date:  2012-06-08

6.  A macroepigenetic approach to identify factors responsible for the autism epidemic in the United States.

Authors:  Renee Dufault; Walter J Lukiw; Raquel Crider; Roseanne Schnoll; David Wallinga; Richard Deth
Journal:  Clin Epigenetics       Date:  2012-04-10       Impact factor: 6.551

7.  Quantitative trait loci for interhemispheric commissure development and social behaviors in the BTBR T⁺ tf/J mouse model of autism.

Authors:  Dorothy M Jones-Davis; Mu Yang; Eric Rider; Nathan C Osbun; Gilberto J da Gente; Jiang Li; Adam M Katz; Michael D Weber; Saunak Sen; Jacqueline Crawley; Elliott H Sherr
Journal:  PLoS One       Date:  2013-04-15       Impact factor: 3.240

8.  The neuron-specific chromatin regulatory subunit BAF53b is necessary for synaptic plasticity and memory.

Authors:  Annie Vogel-Ciernia; Dina P Matheos; Ruth M Barrett; Enikö A Kramár; Soraya Azzawi; Yuncai Chen; Christophe N Magnan; Michael Zeller; Angelina Sylvain; Jakob Haettig; Yousheng Jia; Anthony Tran; Richard Dang; Rebecca J Post; Meredith Chabrier; Alex H Babayan; Jiang I Wu; Gerald R Crabtree; Pierre Baldi; Tallie Z Baram; Gary Lynch; Marcelo A Wood
Journal:  Nat Neurosci       Date:  2013-03-24       Impact factor: 24.884

9.  General developmental health in the VPA-rat model of autism.

Authors:  Mônica R Favre; Tania R Barkat; Deborah Lamendola; Georges Khazen; Henry Markram; Kamila Markram
Journal:  Front Behav Neurosci       Date:  2013-07-24       Impact factor: 3.558

10.  Epigenetic control and cancer: the potential of histone demethylases as therapeutic targets.

Authors:  Fernando Lizcano; Jeison Garcia
Journal:  Pharmaceuticals (Basel)       Date:  2012-09-12
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