Literature DB >> 21289142

Mutation detection and accurate diagnosis of extensively drug-resistant tuberculosis: report from a tertiary care center in India.

Kanchan Ajbani1, Camilla Rodrigues, Shubhada Shenai, Ajita Mehta.   

Abstract

We screened and spoligotyped 150 consecutive phenotypically confirmed extensively drug-resistant Mycobacterium tuberculosis (XDR-TB) isolates (January 2008 to March 2009) for rifampin, isoniazid, fluoroquinolone, and aminoglycoside resistance targeting rpoB, inhA, katG, gyrA, gyrB, and rrs. Mutations predominant among XDR-TB were S315T (katG) (100% of isolates), S531L (rpoB) (97% of isolates), D94G (gyrA) (53% of isolates), and A1401G (rrs) (71% of isolates). Spoligotyping revealed 62% of the isolates to be Beijing.

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Year:  2011        PMID： 21289142      PMCID： PMC3122820          DOI： 10.1128/JCM.00113-11

Source DB:  PubMed          Journal:  J Clin Microbiol        ISSN： 0095-1137            Impact factor:   5.948


  28 in total

1.  Genetic analysis of extensively drug-resistant Mycobacterium tuberculosis strains in Lisbon, Portugal.

Authors:  João Perdigão; Rita Macedo; Ana Malaquias; Ana Ferreira; Laura Brum; Isabel Portugal
Journal:  J Antimicrob Chemother       Date:  2009-12-22       Impact factor: 5.790

2.  Mechanism of resistance to amikacin and kanamycin in Mycobacterium tuberculosis.

Authors:  G J Alangaden; B N Kreiswirth; A Aouad; M Khetarpal; F R Igno; S L Moghazeh; E K Manavathu; S A Lerner
Journal:  Antimicrob Agents Chemother       Date:  1998-05       Impact factor: 5.191

3.  Detection of kanamycin-resistant Mycobacterium tuberculosis by identifying mutations in the 16S rRNA gene.

Authors:  Y Suzuki; C Katsukawa; A Tamaru; C Abe; M Makino; Y Mizuguchi; H Taniguchi
Journal:  J Clin Microbiol       Date:  1998-05       Impact factor: 5.948

4.  Occurrence and stability of insertion sequences in Mycobacterium tuberculosis complex strains: evaluation of an insertion sequence-dependent DNA polymorphism as a tool in the epidemiology of tuberculosis.

Authors:  D van Soolingen; P W Hermans; P E de Haas; D R Soll; J D van Embden
Journal:  J Clin Microbiol       Date:  1991-11       Impact factor: 5.948

5.  Cross-resistant relationships among the aminoglucoside antibiotics in Mycobacterium tuberculosis.

Authors:  M Tsukamura; S Mizuno
Journal:  J Gen Microbiol       Date:  1975-06

6.  Cloning and nucleotide sequence of Mycobacterium tuberculosis gyrA and gyrB genes and detection of quinolone resistance mutations.

Authors:  H E Takiff; L Salazar; C Guerrero; W Philipp; W M Huang; B Kreiswirth; S T Cole; W R Jacobs; A Telenti
Journal:  Antimicrob Agents Chemother       Date:  1994-04       Impact factor: 5.191

7.  Gyrase mutations in laboratory-selected, fluoroquinolone-resistant mutants of Mycobacterium tuberculosis H37Ra.

Authors:  T Kocagöz; C J Hackbarth; I Unsal; E Y Rosenberg; H Nikaido; H F Chambers
Journal:  Antimicrob Agents Chemother       Date:  1996-08       Impact factor: 5.191

8.  Multiplex PCR amplimer conformation analysis for rapid detection of gyrA mutations in fluoroquinolone-resistant Mycobacterium tuberculosis clinical isolates.

Authors:  Augustine F B Cheng; Wing W Yew; Edward W C Chan; Miu L Chin; Mamie M M Hui; Raphael C Y Chan
Journal:  Antimicrob Agents Chemother       Date:  2004-02       Impact factor: 5.191

9.  Characterization of fluoroquinolone-resistant mutant strains of Mycobacterium tuberculosis selected in the laboratory and isolated from patients.

Authors:  G J Alangaden; E K Manavathu; S B Vakulenko; N M Zvonok; S A Lerner
Journal:  Antimicrob Agents Chemother       Date:  1995-08       Impact factor: 5.191

Review 10.  The molecular basis of resistance to isoniazid, rifampin, and pyrazinamide in Mycobacterium tuberculosis.

Authors:  A Somoskovi; L M Parsons; M Salfinger
Journal:  Respir Res       Date:  2001-04-05
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  22 in total

1.  Rapid diagnosis of extensively drug-resistant tuberculosis by use of a reverse line blot hybridization assay.

Authors:  Kanchan Ajbani; Anjali Shetty; Ajita Mehta; Camilla Rodrigues
Journal:  J Clin Microbiol       Date:  2011-05-25       Impact factor: 5.948

2.  A virtual screen discovers novel, fragment-sized inhibitors of Mycobacterium tuberculosis InhA.

Authors:  Alexander L Perryman; Weixuan Yu; Xin Wang; Sean Ekins; Stefano Forli; Shao-Gang Li; Joel S Freundlich; Peter J Tonge; Arthur J Olson
Journal:  J Chem Inf Model       Date:  2015-02-17       Impact factor: 4.956

3.  Characterization of Mutations Conferring Resistance to Rifampin in Mycobacterium tuberculosis Clinical Strains.

Authors:  Tomasz Jagielski; Zofia Bakuła; Anna Brzostek; Alina Minias; Radosław Stachowiak; Joanna Kalita; Agnieszka Napiórkowska; Ewa Augustynowicz-Kopeć; Anna Żaczek; Edita Vasiliauskiene; Jacek Bielecki; Jarosław Dziadek
Journal:  Antimicrob Agents Chemother       Date:  2018-09-24       Impact factor: 5.191

4.  Molecular characterization of multidrug-resistant Mycobacterium tuberculosis isolates from China.

Authors:  Li-Li Zhao; Yan Chen; Hai-Can Liu; Qiang Xia; Xiao-Cui Wu; Qing Sun; Xiu-Qin Zhao; Gui-Lian Li; Zhi-Guang Liu; Kang-Lin Wan
Journal:  Antimicrob Agents Chemother       Date:  2014-01-13       Impact factor: 5.191

5.  Phenotypic and genotypic diversity in a multinational sample of drug-resistant Mycobacterium tuberculosis isolates.

Authors:  R S Garfein; D G Catanzaro; T C Rodwell; E Avalos; R L Jackson; J Kaping; H Evasco; C Rodrigues; V Crudu; S-Y G Lin; E Groessl; E Groessel; N Hillery; A Trollip; T Ganiats; T C Victor; K Eisenach; F Valafar; J Channick; L Qian; A Catanzaro
Journal:  Int J Tuberc Lung Dis       Date:  2015-04       Impact factor: 2.373

6.  Characterization of mutations conferring extensive drug resistance to Mycobacterium tuberculosis isolates in Pakistan.

Authors:  Asho Ali; Rumina Hasan; Kauser Jabeen; Nusrat Jabeen; Ejaz Qadeer; Zahra Hasan
Journal:  Antimicrob Agents Chemother       Date:  2011-09-12       Impact factor: 5.191

Review 7.  Global control of tuberculosis: from extensively drug-resistant to untreatable tuberculosis.

Authors:  Keertan Dheda; Tawanda Gumbo; Neel R Gandhi; Megan Murray; Grant Theron; Zarir Udwadia; G B Migliori; Robin Warren
Journal:  Lancet Respir Med       Date:  2014-03-24       Impact factor: 30.700

8.  Molecular characterization of multidrug- and extensively drug-resistant Mycobacterium tuberculosis strains in Jiangxi, China.

Authors:  Xiaoliang Yuan; Tiantuo Zhang; Kazuyoshi Kawakami; Jiaxin Zhu; Hongtao Li; Jianping Lei; Shaohua Tu
Journal:  J Clin Microbiol       Date:  2012-05-02       Impact factor: 5.948

9.  Molecular diagnosis of fluoroquinolone resistance in Mycobacterium tuberculosis.

Authors:  Christine Bernard; Nicolas Veziris; Florence Brossier; Wladimir Sougakoff; Vincent Jarlier; Jérôme Robert; Alexandra Aubry
Journal:  Antimicrob Agents Chemother       Date:  2014-12-22       Impact factor: 5.191

10.  Determination of MICs of levofloxacin for Mycobacterium tuberculosis with gyrA mutations.

Authors:  P Kambli; K Ajbani; C Nikam; A Khillari; A Shetty; Z Udwadia; S B Georghiou; T C Rodwell; A Catanzaro; C Rodrigues
Journal:  Int J Tuberc Lung Dis       Date:  2015-10       Impact factor: 2.373
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