Literature DB >> 21288925

A new mechanism for blocking myeloid-derived suppressor cells by CpG.

Melissa G Lechner1, Alan L Epstein.   

Abstract

In this issue of Clinical Cancer Research, Zoglmeier and colleagues show that CpG, via the induction of IFN-α, matures myeloid-derived suppressor cells to abrogate immune suppression in 2 murine solid tumor models.

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Year:  2011        PMID: 21288925      PMCID: PMC4237605          DOI: 10.1158/1078-0432.CCR-11-0024

Source DB:  PubMed          Journal:  Clin Cancer Res        ISSN: 1078-0432            Impact factor:   12.531


  18 in total

Review 1.  CpG motifs: the active ingredient in bacterial extracts?

Authors:  Arthur M Krieg
Journal:  Nat Med       Date:  2003-07       Impact factor: 53.440

Review 2.  Toll-like receptors in tumor immunotherapy.

Authors:  Chrystal M Paulos; Andrew Kaiser; Claudia Wrzesinski; Christian S Hinrichs; Lydie Cassard; Andrea Boni; Pawel Muranski; Luis Sanchez-Perez; Douglas C Palmer; Zhiya Yu; Paul A Antony; Luca Gattinoni; Steven A Rosenberg; Nicholas P Restifo
Journal:  Clin Cancer Res       Date:  2007-09-15       Impact factor: 12.531

3.  CpG DNA: a potent signal for growth, activation, and maturation of human dendritic cells.

Authors:  G Hartmann; G J Weiner; A M Krieg
Journal:  Proc Natl Acad Sci U S A       Date:  1999-08-03       Impact factor: 11.205

4.  A common pathway mediated through Toll-like receptors leads to T- and natural killer-cell immunosuppression.

Authors:  Ilan Vaknin; Liora Blinder; Lynn Wang; Roi Gazit; Elena Shapira; Olga Genina; Mark Pines; Eli Pikarsky; Michal Baniyash
Journal:  Blood       Date:  2007-11-08       Impact factor: 22.113

5.  Sunitinib mediates reversal of myeloid-derived suppressor cell accumulation in renal cell carcinoma patients.

Authors:  Jennifer S Ko; Arnold H Zea; Brian I Rini; Joanna L Ireland; Paul Elson; Peter Cohen; Ali Golshayan; Patricia A Rayman; Laura Wood; Jorge Garcia; Robert Dreicer; Ronald Bukowski; James H Finke
Journal:  Clin Cancer Res       Date:  2009-03-10       Impact factor: 12.531

6.  Membrane-associated Hsp72 from tumor-derived exosomes mediates STAT3-dependent immunosuppressive function of mouse and human myeloid-derived suppressor cells.

Authors:  Fanny Chalmin; Sylvain Ladoire; Grégoire Mignot; Julie Vincent; Mélanie Bruchard; Jean-Paul Remy-Martin; Wilfrid Boireau; Alain Rouleau; Benoit Simon; David Lanneau; Aurélie De Thonel; Gabriele Multhoff; Arlette Hamman; François Martin; Bruno Chauffert; Eric Solary; Laurence Zitvogel; Carmen Garrido; Bernhard Ryffel; Christophe Borg; Lionel Apetoh; Cédric Rébé; François Ghiringhelli
Journal:  J Clin Invest       Date:  2010-01-19       Impact factor: 14.808

7.  Mechanism of all-trans retinoic acid effect on tumor-associated myeloid-derived suppressor cells.

Authors:  Yulia Nefedova; Mayer Fishman; Simon Sherman; Xingyu Wang; Amer A Beg; Dmitry I Gabrilovich
Journal:  Cancer Res       Date:  2007-11-15       Impact factor: 12.701

8.  Gemcitabine directly inhibits myeloid derived suppressor cells in BALB/c mice bearing 4T1 mammary carcinoma and augments expansion of T cells from tumor-bearing mice.

Authors:  Hanh K Le; Laura Graham; Esther Cha; Johanna K Morales; Masoud H Manjili; Harry D Bear
Journal:  Int Immunopharmacol       Date:  2009-03-29       Impact factor: 4.932

9.  Immune signatures of murine and human cancers reveal unique mechanisms of tumor escape and new targets for cancer immunotherapy.

Authors:  Rebecca E Sadun; Suzanne M Sachsman; Xiaoying Chen; Kamilee W Christenson; William Z Morris; Peisheng Hu; Alan L Epstein
Journal:  Clin Cancer Res       Date:  2007-07-01       Impact factor: 12.531

10.  Phosphodiesterase-5 inhibition augments endogenous antitumor immunity by reducing myeloid-derived suppressor cell function.

Authors:  Paolo Serafini; Kristen Meckel; Michael Kelso; Kimberly Noonan; Joseph Califano; Wayne Koch; Luigi Dolcetti; Vincenzo Bronte; Ivan Borrello
Journal:  J Exp Med       Date:  2006-11-13       Impact factor: 14.307

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  8 in total

Review 1.  Is cancer vaccination feasible at older age?

Authors:  Claudia Gravekamp; Arthee Jahangir
Journal:  Exp Gerontol       Date:  2014-02-06       Impact factor: 4.032

Review 2.  Chemokines, costimulatory molecules and fusion proteins for the immunotherapy of solid tumors.

Authors:  Melissa G Lechner; Sarah M Russell; Rikki S Bass; Alan L Epstein
Journal:  Immunotherapy       Date:  2011-11       Impact factor: 4.196

Review 3.  The impact of aging on cancer vaccination.

Authors:  Claudia Gravekamp
Journal:  Curr Opin Immunol       Date:  2011-07-18       Impact factor: 7.486

4.  Induction of liver-specific intrahepatic myeloid cells aggregation expands CD8 T cell and inhibits growth of murine hepatoma.

Authors:  Yung-Chang Lin; Chen-Yu Hsu; Sheng-Kai Huang; Yun-Han Fan; Chien-Hao Huang; Chan-Keng Yang; Wan-Ting Su; Po-Chia Chang; Avijit Dutta; Yu-Jen Liu; Ching-Tai Huang; Tse-Ching Chen; Chun-Yen Lin
Journal:  Oncoimmunology       Date:  2018-09-19       Impact factor: 8.110

Review 5.  Aging and cancer vaccines.

Authors:  Claudia Gravekamp; Dinesh Chandra
Journal:  Crit Rev Oncog       Date:  2013

6.  Immunogenicity of murine solid tumor models as a defining feature of in vivo behavior and response to immunotherapy.

Authors:  Melissa G Lechner; Saman S Karimi; Keegan Barry-Holson; Trevor E Angell; Katherine A Murphy; Connor H Church; John R Ohlfest; Peisheng Hu; Alan L Epstein
Journal:  J Immunother       Date:  2013 Nov-Dec       Impact factor: 4.456

7.  Functional characterization of human Cd33+ and Cd11b+ myeloid-derived suppressor cell subsets induced from peripheral blood mononuclear cells co-cultured with a diverse set of human tumor cell lines.

Authors:  Melissa G Lechner; Carolina Megiel; Sarah M Russell; Brigid Bingham; Nicholas Arger; Tammy Woo; Alan L Epstein
Journal:  J Transl Med       Date:  2011-06-09       Impact factor: 5.531

8.  6-Thioguanine-loaded polymeric micelles deplete myeloid-derived suppressor cells and enhance the efficacy of T cell immunotherapy in tumor-bearing mice.

Authors:  Laura Jeanbart; Iraklis C Kourtis; André J van der Vlies; Melody A Swartz; Jeffrey A Hubbell
Journal:  Cancer Immunol Immunother       Date:  2015-05-16       Impact factor: 6.968

  8 in total

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