| Literature DB >> 12835699 |
Abstract
The use of bacteria and bacterial extracts for immunotherapy has a checkered past. Recent developments in immunology reveal that these nonspecific immune activators actually work by triggering specific receptors that are expressed by subsets of immune cells. Identification of these receptors and the molecular signaling pathways that they activate has enabled a new era of specific targeted immunotherapy using chemically synthesized mimics of pathogen molecules.Mesh：
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Year: 2003 PMID： 12835699 DOI： 10.1038/nm0703-831
Source DB: PubMed Journal: Nat Med ISSN： 1078-8956 Impact factor: 53.440