Literature DB >> 21286626

DNA-capped nanoparticles designed for doxorubicin drug delivery.

Colleen M Alexander1, Mathew M Maye, James C Dabrowiak.   

Abstract

The anticancer drug, doxorubicin (DOX), was loaded onto DNA-capped gold nanoparticles (AuNP) designed for specific DOX intercalation. Drug binding was confirmed by monitoring DNA melting temperature, AuNP plasmon resonance maximum, and hydrodynamic radius increase, as a function of [DOX]/[DNA] ratio. The capacity for drug release to target DNA was confirmed.

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Year:  2011        PMID： 21286626     DOI： 10.1039/c0cc04916f

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  10 in total

Review 1.  Gold nanoparticles: preparation, properties, and applications in bionanotechnology.

Authors:  Yi-Cheun Yeh; Brian Creran; Vincent M Rotello
Journal:  Nanoscale       Date:  2011-11-10       Impact factor: 7.790

Review 2.  Engineering artificial machines from designable DNA materials for biomedical applications.

Authors:  Hao Qi; Guoyou Huang; Yulong Han; Xiaohui Zhang; Yuhui Li; Belinda Pingguan-Murphy; Tian Jian Lu; Feng Xu; Lin Wang
Journal:  Tissue Eng Part B Rev       Date:  2015-02-09       Impact factor: 6.389

3.  Determination of Zeta Potential via Nanoparticle Translocation Velocities through a Tunable Nanopore: Using DNA-modified Particles as an Example.

Authors:  Emma L C J Blundell; Robert Vogel; Mark Platt
Journal:  J Vis Exp       Date:  2016-10-26       Impact factor: 1.355

Review 4.  Phase-shift, stimuli-responsive drug carriers for targeted delivery.

Authors:  Brian E O'Neill; Natalya Rapoport
Journal:  Ther Deliv       Date:  2011-09

5.  In vitro clearance of doxorubicin with a DNA-based filtration device designed for intravascular use with intra-arterial chemotherapy.

Authors:  Mariam S Aboian; Jay F Yu; Ayushi Gautam; Chia-Hung Sze; Jeffrey K Yang; Jonathan Chan; Prasheel V Lillaney; Caroline D Jordan; Hee-Jeung Oh; David M Wilson; Anand S Patel; Mark W Wilson; Steven W Hetts
Journal:  Biomed Microdevices       Date:  2016-12       Impact factor: 2.838

6.  DNA Polyplexes as Combinatory Drug Carriers of Doxorubicin and Cisplatin: An in Vitro Study.

Authors:  Han Chang Kang; Hana Cho; You Han Bae
Journal:  Mol Pharm       Date:  2015-07-13       Impact factor: 4.939

7.  Switchable Fluorescence of Doxorubicin for Label-Free Imaging of Bioorthogonal Drug Release.

Authors:  Taha Bilal Uyar; Kui Wu; Muhan He; Irfan Khan; Maksim Royzen; Mehmet V Yigit
Journal:  ChemMedChem       Date:  2020-04-17       Impact factor: 3.466

8.  Understanding structural and molecular properties of complexes of nucleobases and Au13 golden nanocluster by DFT calculations and DFT-MD simulation.

Authors:  Ghazaleh Hashemkhani Shahnazari; Masoud Darvish Ganji
Journal:  Sci Rep       Date:  2021-01-11       Impact factor: 4.379

9.  Terminal PEGylated DNA-Gold Nanoparticle Conjugates Offering High Resistance to Nuclease Degradation and Efficient Intracellular Delivery of DNA Binding Agents.

Authors:  Lei Song; Yuan Guo; Deborah Roebuck; Chun Chen; Min Yang; Zhongqiang Yang; Sreejesh Sreedharan; Caroline Glover; Jim A Thomas; Dongsheng Liu; Shengrong Guo; Rongjun Chen; Dejian Zhou
Journal:  ACS Appl Mater Interfaces       Date:  2015-08-13       Impact factor: 9.229

10.  Mild two-step method to construct DNA-conjugated silicon nanoparticles: scaffolds for the detection of microRNA-21.

Authors:  Xiaoye Su; Li Kuang; Cooper Battle; Ted Shaner; Brian S Mitchell; Mark J Fink; Janarthanan Jayawickramarajah
Journal:  Bioconjug Chem       Date:  2014-09-26       Impact factor: 4.774
  10 in total

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