Literature DB >> 21283084

The inv(3)(q21q26)/t(3;3)(q21;q26) is frequently accompanied by alterations of the RUNX1, KRAS and NRAS and NF1 genes and mediates adverse prognosis both in MDS and in AML: a study in 39 cases of MDS or AML.

C Haferlach, U Bacher, T Haferlach, F Dicker, T Alpermann, W Kern, S Schnittger.   

Abstract

Entities:  

Mesh:

Substances:

Year:  2011        PMID: 21283084     DOI: 10.1038/leu.2011.5

Source DB:  PubMed          Journal:  Leukemia        ISSN: 0887-6924            Impact factor:   11.528


× No keyword cloud information.
  11 in total

1.  EVI1-rearranged acute myeloid leukemias are characterized by distinct molecular alterations.

Authors:  Vincent-Philippe Lavallée; Patrick Gendron; Sébastien Lemieux; Giovanni D'Angelo; Josée Hébert; Guy Sauvageau
Journal:  Blood       Date:  2014-10-20       Impact factor: 22.113

2.  Screening of mutations in the additional sex combs like 1, transcriptional regulator, tumor protein p53, and KRAS proto-oncogene, GTPase/NRAS proto-oncogene, GTPase genes of patients with myelodysplastic syndrome.

Authors:  Carolina Leite; Lucas Delmonico; Gilda Alves; Romario José Gomes; Mariana Rodrigues Martino; Aline Rodrigues da Silva; Aline Dos Santos Moreira; Maria Christina Maioli; Luciano Rios Scherrer; Elenice Ferreira Bastos; Roberto Irineu; Maria Helena Ornellas
Journal:  Biomed Rep       Date:  2017-08-09

Review 3.  [Myelodysplastic syndromes. Epidemiology, molecular and morphological characteristics and risk stratification].

Authors:  A H Schmitt-Graeff; M J Müller; P Fisch
Journal:  Pathologe       Date:  2013-02       Impact factor: 1.011

4.  Complex or monosomal karyotype and not blast percentage is associated with poor survival in acute myeloid leukemia and myelodysplastic syndrome patients with inv(3)(q21q26.2)/t(3;3)(q21;q26.2): a Bone Marrow Pathology Group study.

Authors:  Heesun J Rogers; James W Vardiman; John Anastasi; Gordana Raca; Natasha M Savage; Athena M Cherry; Daniel Arber; Erika Moore; Jennifer J D Morrissette; Adam Bagg; Yen-Chun Liu; Susan Mathew; Attilio Orazi; Pei Lin; Sa A Wang; Carlos E Bueso-Ramos; Kathryn Foucar; Robert P Hasserjian; Ramon V Tiu; Matthew Karafa; Eric D Hsi
Journal:  Haematologica       Date:  2014-01-24       Impact factor: 9.941

5.  Clinical and prognostic significance of 3q26.2 and other chromosome 3 abnormalities in CML in the era of tyrosine kinase inhibitors.

Authors:  Wei Wang; Jorge E Cortes; Pei Lin; Michael W Beaty; Di Ai; Hesham M Amin; Timothy J McDonnell; Chi Young Ok; Hagop M Kantarjian; L Jeffrey Medeiros; Shimin Hu
Journal:  Blood       Date:  2015-08-04       Impact factor: 22.113

Review 6.  The genetic basis of phenotypic heterogeneity in myelodysplastic syndromes.

Authors:  Azra Raza; Naomi Galili
Journal:  Nat Rev Cancer       Date:  2012-12       Impact factor: 60.716

7.  Mutational spectrum of myeloid malignancies with inv(3)/t(3;3) reveals a predominant involvement of RAS/RTK signaling pathways.

Authors:  Stefan Gröschel; Mathijs A Sanders; Remco Hoogenboezem; Annelieke Zeilemaker; Marije Havermans; Claudia Erpelinck; Eric M J Bindels; H Berna Beverloo; Hartmut Döhner; Bob Löwenberg; Konstanze Döhner; Ruud Delwel; Peter J M Valk
Journal:  Blood       Date:  2014-11-07       Impact factor: 22.113

Review 8.  EVI1 dysregulation: impact on biology and therapy of myeloid malignancies.

Authors:  Christine Birdwell; Warren Fiskus; Tapan M Kadia; Courtney D DiNardo; Christopher P Mill; Kapil N Bhalla
Journal:  Blood Cancer J       Date:  2021-03-22       Impact factor: 11.037

9.  EVI1 and GATA2 misexpression induced by inv(3)(q21q26) contribute to megakaryocyte-lineage skewing and leukemogenesis.

Authors:  Ayaka Yamaoka; Mikiko Suzuki; Saori Katayama; Daiki Orihara; James Douglas Engel; Masayuki Yamamoto
Journal:  Blood Adv       Date:  2020-04-28

10.  Gene expression patterns of hemizygous and heterozygous KIT mutations suggest distinct oncogenic pathways: a study in NIH3T3 cell lines and GIST samples.

Authors:  Jean-Baptiste Bachet; Séverine Tabone-Eglinger; Sophie Dessaux; Anthony Besse; Sabrina Brahimi-Adouane; Jean-François Emile; Jean-Yves Blay; Laurent Alberti
Journal:  PLoS One       Date:  2013-04-12       Impact factor: 3.240

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.