Literature DB >> 2128277

Degranulation of human neutrophils after exposure to bacterial phospholipase C.

T K Wazny1, N Mummaw, B Styrt.   

Abstract

Because an endogenous phospholipase C (PLC) participates in neutrophil activation and because many bacterial pathogens produce PLCs, these studies examined the effect of PLC from Bacillus cereus on the release of the granule enzyme lysozyme from human neutrophils. Bacillus cereus PLC caused dose-dependent lysozyme release, and combined stimulation of neutrophils with PLC and fluoride led to increased secretion. Stimulation of neutrophil degranulation is a potential contributing factor for tissue damage in infections caused by PLC-producing organisms.

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Year:  1990        PMID： 2128277     DOI： 10.1007/bf01967385

Source DB:  PubMed          Journal:  Eur J Clin Microbiol Infect Dis        ISSN： 0934-9723            Impact factor:   3.267


  8 in total

1.  Stimulation of the respiration of polymorphonuclear leucocytes by phospholipase C.

Authors:  P Patriarca; M Zatti; R Cramer; F Rossi
Journal:  Life Sci I       Date:  1970-08-01

2.  Effects of alpha and theta toxins from Clostridium perfringens on human polymorphonuclear leukocytes.

Authors:  D L Stevens; J Mitten; C Henry
Journal:  J Infect Dis       Date:  1987-08       Impact factor: 5.226

3.  Differential lysis of plasma membranes and granules of human neutrophils by digitonin.

Authors:  B Styrt; P C Johnson; M S Klempner
Journal:  Tissue Cell       Date:  1985       Impact factor: 2.466

4.  Independence with respect to Ca2+ changes of the neutrophil respiratory and secretory response to exogenous phospholipase C and possible involvement of diacylglycerol and protein kinase C.

Authors:  M Grzeskowiak; V Della Bianca; P De Togni; E Papini; F Rossi
Journal:  Biochim Biophys Acta       Date:  1985-01-18

5.  Neutrophil oxidative metabolism after exposure to bacterial phospholipase C.

Authors:  B Styrt; R D Walker; J C White
Journal:  J Lab Clin Med       Date:  1989-07

6.  Serious infections caused by Bacillus species.

Authors:  R Sliman; S Rehm; D M Shlaes
Journal:  Medicine (Baltimore)       Date:  1987-05       Impact factor: 1.889

7.  Role of a guanine nucleotide regulatory protein in the activation of phospholipase C by different chemoattractants.

Authors:  M W Verghese; L Charles; L Jakoi; S B Dillon; R Snyderman
Journal:  J Immunol       Date:  1987-06-15       Impact factor: 5.422

Review 8.  Posttraumatic endophthalmitis: the emerging role of Bacillus cereus infection.

Authors:  R T Davey; W B Tauber
Journal:  Rev Infect Dis       Date:  1987 Jan-Feb
  8 in total
  3 in total

Review 1.  Potential role of phospholipases in virulence and fungal pathogenesis.

Authors:  M A Ghannoum
Journal:  Clin Microbiol Rev       Date:  2000-01       Impact factor: 26.132

2.  Survival and germination of Bacillus cereus spores without outgrowth or enterotoxin production during in vitro simulation of gastrointestinal transit.

Authors:  Siele Ceuppens; Mieke Uyttendaele; Katrien Drieskens; Marc Heyndrickx; Andreja Rajkovic; Nico Boon; Tom Van de Wiele
Journal:  Appl Environ Microbiol       Date:  2012-08-24       Impact factor: 4.792

Review 3.  Bacillus cereus and related species.

Authors:  F A Drobniewski
Journal:  Clin Microbiol Rev       Date:  1993-10       Impact factor: 26.132
  3 in total

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