| Literature DB >> 21281649 |
Werner Friedland1, Michael Dingfelder, Pavel Kundrát, Peter Jacob.
Abstract
This review describes the PARTRAC suite of comprehensive Monte Carlo simulation tools for calculations of track structures of a variety of ionizing radiation qualities and their biological effects. A multi-scale target model characterizes essential structures of the whole genomic DNA within human fibroblasts and lymphocytes in atomic resolution. Calculation methods and essential results are recapitulated regarding the physical, physico-chemical and chemical stage of track structure development of radiation damage induction. Recent model extension towards DNA repair processes extends the time dimension by about 12 orders of magnitude and paves the way for superior predictions of radiation risks. 2011 Elsevier B.V. All rights reserved.Entities:
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Year: 2011 PMID： 21281649 DOI： 10.1016/j.mrfmmm.2011.01.003
Source DB: PubMed Journal: Mutat Res ISSN： 0027-5107 Impact factor: 2.433