BACKGROUND: Midgut carcinoids are neuroendocrine tumors that commonly metastasize to the intestinal mesentery, where they predispose to intestinal obstruction, ischemia and/or congestion. Because of their location, many mesenteric carcinoid tumors are deemed unresectable due to the risk of uncontrollable bleeding and prolonged intestinal ischemia. CASE PRESENTATION: We report the case of a 60-year-old male with a mesenteric carcinoid tumor obstructing his superior mesenteric vein, resulting in intestinal varices and severe recurrent GI bleeds. While his tumor was thought to be unresectable by conventional techniques, it was successfully resected using intestinal autotransplantation to safely gain access to the tumor. This case is the first described application of this technique to carcinoid tumors. CONCLUSIONS: Intestinal autotransplantation can be utilized to safely resect mesenteric carcinoid tumors from patients who were not previously thought to be surgical candidates. We review the literature concerning both carcinoid metastases to the intestinal mesentery and the use of intestinal autotransplantation to treat lesions involving the mesenteric root.
BACKGROUND: Midgut carcinoids are neuroendocrine tumors that commonly metastasize to the intestinal mesentery, where they predispose to intestinal obstruction, ischemia and/or congestion. Because of their location, many mesenteric carcinoid tumors are deemed unresectable due to the risk of uncontrollable bleeding and prolonged intestinal ischemia. CASE PRESENTATION: We report the case of a 60-year-old male with a mesenteric carcinoid tumor obstructing his superior mesenteric vein, resulting in intestinal varices and severe recurrent GI bleeds. While his tumor was thought to be unresectable by conventional techniques, it was successfully resected using intestinal autotransplantation to safely gain access to the tumor. This case is the first described application of this technique to carcinoid tumors. CONCLUSIONS: Intestinal autotransplantation can be utilized to safely resect mesenteric carcinoid tumors from patients who were not previously thought to be surgical candidates. We review the literature concerning both carcinoid metastases to the intestinal mesentery and the use of intestinal autotransplantation to treat lesions involving the mesenteric root.
Authors: Andreas G Tzakis; Panagiotis Tryphonopoulos; Werviston De Faria; Tomoaki Kato; Seigo Nishida; David M Levi; Juan Madariaga; Debbie Weppler; Naveen Mittal; Phillip Ruiz; Jose R Nevy; John F Thompson Journal: J Am Coll Surg Date: 2003-11 Impact factor: 6.113
Authors: Per Hellman; Ola Hessman; Göran Akerström; Peter Stålberg; Joakim Hennings; Martin Björck; L-G Eriksson Journal: World J Surg Date: 2010-06 Impact factor: 3.352
Authors: S Nikeghbalian; M Aliakbarian; K Kazemi; A R Shamsaeefar; S H Mehdi; A Bahreini; S A Malek-Hosseini Journal: Int J Organ Transplant Med Date: 2014