Literature DB >> 21278743

Codon adaptation-based control of protein expression in C. elegans.

Stefanie Redemann1, Siegfried Schloissnig, Susanne Ernst, Andrey Pozniakowsky, Swathi Ayloo, Antony A Hyman, Henrik Bringmann.   

Abstract

We present a method to control protein levels under native genetic regulation in Caenorhabditis elegans by using synthetic genes with adapted codons. We found that the force acting on the spindle in C. elegans embryos was related to the amount of the G-protein regulator GPR-1/2. Codon-adapted versions of any C. elegans gene can be designed using our web tool, C. elegans codon adapter.

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Year:  2011        PMID： 21278743     DOI： 10.1038/nmeth.1565

Source DB:  PubMed          Journal:  Nat Methods        ISSN： 1548-7091            Impact factor:   28.547


  22 in total

1.  Translation of polarity cues into asymmetric spindle positioning in Caenorhabditis elegans embryos.

Authors:  Kelly Colombo; Stephan W Grill; Randall J Kimple; Francis S Willard; David P Siderovski; Pierre Gönczy
Journal:  Science       Date:  2003-05-15       Impact factor: 47.728

2.  Spindle oscillations during asymmetric cell division require a threshold number of active cortical force generators.

Authors:  Jacques Pecreaux; Jens-Christian Röper; Karsten Kruse; Frank Jülicher; Anthony A Hyman; Stephan W Grill; Jonathon Howard
Journal:  Curr Biol       Date:  2006-11-07       Impact factor: 10.834

3.  The Synthetic Gene Designer: a flexible web platform to explore sequence manipulation for heterologous expression.

Authors:  Gang Wu; Nabila Bashir-Bello; Stephen J Freeland
Journal:  Protein Expr Purif       Date:  2005-11-15       Impact factor: 1.650

4.  The codon Adaptation Index--a measure of directional synonymous codon usage bias, and its potential applications.

Authors:  P M Sharp; W H Li
Journal:  Nucleic Acids Res       Date:  1987-02-11       Impact factor: 16.971

5.  Co-variation of tRNA abundance and codon usage in Escherichia coli at different growth rates.

Authors:  H Dong; L Nilsson; C G Kurland
Journal:  J Mol Biol       Date:  1996-08-02       Impact factor: 5.469

6.  Toward improving Caenorhabditis elegans phenome mapping with an ORFeome-based RNAi library.

Authors:  Jean-François Rual; Julian Ceron; John Koreth; Tong Hao; Anne-Sophie Nicot; Tomoko Hirozane-Kishikawa; Jean Vandenhaute; Stuart H Orkin; David E Hill; Sander van den Heuvel; Marc Vidal
Journal:  Genome Res       Date:  2004-10       Impact factor: 9.043

7.  Splice site prediction in Arabidopsis thaliana pre-mRNA by combining local and global sequence information.

Authors:  S M Hebsgaard; P G Korning; N Tolstrup; J Engelbrecht; P Rouzé; S Brunak
Journal:  Nucleic Acids Res       Date:  1996-09-01       Impact factor: 16.971

8.  Coding-sequence determinants of gene expression in Escherichia coli.

Authors:  Grzegorz Kudla; Andrew W Murray; David Tollervey; Joshua B Plotkin
Journal:  Science       Date:  2009-04-10       Impact factor: 47.728

9.  Asymmetrically distributed C. elegans homologs of AGS3/PINS control spindle position in the early embryo.

Authors:  Monica Gotta; Yan Dong; Yuri K Peterson; Stephen M Lanier; Julie Ahringer
Journal:  Curr Biol       Date:  2003-06-17       Impact factor: 10.834

10.  The genetics of Caenorhabditis elegans.

Authors:  S Brenner
Journal:  Genetics       Date:  1974-05       Impact factor: 4.562
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  77 in total

1.  Cas9 Variants Expand the Target Repertoire in Caenorhabditis elegans.

Authors:  Ryan T Bell; Becky X H Fu; Andrew Z Fire
Journal:  Genetics       Date:  2015-12-17       Impact factor: 4.562

2.  Dynamic localization of C. elegans TPR-GoLoco proteins mediates mitotic spindle orientation by extrinsic signaling.

Authors:  Adam D Werts; Minna Roh-Johnson; Bob Goldstein
Journal:  Development       Date:  2011-09-08       Impact factor: 6.868

3.  A wake-active locomotion circuit depolarizes a sleep-active neuron to switch on sleep.

Authors:  Elisabeth Maluck; Inka Busack; Judith Besseling; Florentin Masurat; Michal Turek; Karl Emanuel Busch; Henrik Bringmann
Journal:  PLoS Biol       Date:  2020-02-20       Impact factor: 8.029

4.  Superresolution microscopy reveals the three-dimensional organization of meiotic chromosome axes in intact Caenorhabditis elegans tissue.

Authors:  Simone Köhler; Michal Wojcik; Ke Xu; Abby F Dernburg
Journal:  Proc Natl Acad Sci U S A       Date:  2017-05-30       Impact factor: 11.205

5.  Efficient Generation of Endogenous Fluorescent Reporters by Nested CRISPR in Caenorhabditis elegans.

Authors:  Jeremy Vicencio; Carmen Martínez-Fernández; Xènia Serrat; Julián Cerón
Journal:  Genetics       Date:  2019-01-29       Impact factor: 4.562

6.  Local microtubule organization promotes cargo transport in C. elegans dendrites.

Authors:  Martin Harterink; Stacey L Edwards; Bart de Haan; Kah Wai Yau; Sander van den Heuvel; Lukas C Kapitein; Kenneth G Miller; Casper C Hoogenraad
Journal:  J Cell Sci       Date:  2018-10-22       Impact factor: 5.285

7.  Interneurons Regulate Locomotion Quiescence via Cyclic Adenosine Monophosphate Signaling During Stress-Induced Sleep in Caenorhabditis elegans.

Authors:  Alana Cianciulli; Lauren Yoslov; Kristen Buscemi; Nicole Sullivan; Ryan T Vance; Francis Janton; Mary R Szurgot; Thomas Buerkert; Edwin Li; Matthew D Nelson
Journal:  Genetics       Date:  2019-07-10       Impact factor: 4.562

8.  Engineered non-Mendelian inheritance of entire parental genomes in C. elegans.

Authors:  Judith Besseling; Henrik Bringmann
Journal:  Nat Biotechnol       Date:  2016-08-01       Impact factor: 54.908

9.  A lysosomal switch triggers proteostasis renewal in the immortal C. elegans germ lineage.

Authors:  K Adam Bohnert; Cynthia Kenyon
Journal:  Nature       Date:  2017-11-22       Impact factor: 49.962

Review 10.  The Caenorhabditis elegans Transgenic Toolbox.

Authors:  Jeremy Nance; Christian Frøkjær-Jensen
Journal:  Genetics       Date:  2019-08       Impact factor: 4.562
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