| Literature DB >> 2127356 |
T Hirano1, S Akira, T Taga, T Kishimoto.
Abstract
Interleukin 6 (IL-6) is a multi-functional cytokine that is produced by a range of cells and plays a central role in host defense mechanisms. Abnormal production of IL-6 has been suggested to be involved in glomerulonephritis, plasmacytomagenesis and in the pathogenesis of autoimmune diseases. In this review, Toshio Hirano and colleagues discuss the possible involvement of IL-6 in a variety of diseases, the regulatory mechanism(s) of expression of the IL-6 gene and the structure and function of the IL-6 receptor.Entities:
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Year: 1990 PMID： 2127356 DOI： 10.1016/0167-5699(90)90173-7
Source DB: PubMed Journal: Immunol Today ISSN： 0167-5699