Literature DB >> 10944812

Activation of the innate immune system by CpG oligodeoxynucleotides: immunoprotective activity and safety.

D M Klinman1, S Kamstrup, D Verthelyi, I Gursel, K J Ishii, F Takeshita, M Gursel.   

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Year:  2000        PMID: 10944812     DOI: 10.1007/s002810050027

Source DB:  PubMed          Journal:  Springer Semin Immunopathol        ISSN: 0344-4325


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  53 in total

1.  Activation of cutaneous dendritic cells by CpG-containing oligodeoxynucleotides: a role for dendritic cells in the augmentation of Th1 responses by immunostimulatory DNA.

Authors:  T Jakob; P S Walker; A M Krieg; M C Udey; J C Vogel
Journal:  J Immunol       Date:  1998-09-15       Impact factor: 5.422

2.  CpG oligodeoxynucleotides trigger protective and curative Th1 responses in lethal murine leishmaniasis.

Authors:  S Zimmermann; O Egeter; S Hausmann; G B Lipford; M Röcken; H Wagner; K Heeg
Journal:  J Immunol       Date:  1998-04-15       Impact factor: 5.422

3.  Bacterial DNA containing CpG motifs stimulates lymphocyte-dependent protection of mice against lethal infection with intracellular bacteria.

Authors:  K L Elkins; T R Rhinehart-Jones; S Stibitz; J S Conover; D M Klinman
Journal:  J Immunol       Date:  1999-02-15       Impact factor: 5.422

4.  A novel role for B cells in early protective immunity to an intracellular pathogen, Francisella tularensis strain LVS.

Authors:  S J Culkin; T Rhinehart-Jones; K L Elkins
Journal:  J Immunol       Date:  1997-04-01       Impact factor: 5.422

5.  Complexity of the cytokine and antibody response elicited by immunizing mice with Plasmodium yoelii circumsporozoite protein plasmid DNA.

Authors:  G Mor; D M Klinman; S Shapiro; E Hagiwara; M Sedegah; J A Norman; S L Hoffman; A D Steinberg
Journal:  J Immunol       Date:  1995-08-15       Impact factor: 5.422

6.  Pervasive CpG suppression in animal mitochondrial genomes.

Authors:  L R Cardon; C Burge; D A Clayton; S Karlin
Journal:  Proc Natl Acad Sci U S A       Date:  1994-04-26       Impact factor: 11.205

7.  Minimal requirements for murine resistance to infection with Francisella tularensis LVS.

Authors:  K L Elkins; T R Rhinehart-Jones; S J Culkin; D Yee; R K Winegar
Journal:  Infect Immun       Date:  1996-08       Impact factor: 3.441

8.  Bacterial DNA induces NK cells to produce IFN-gamma in vivo and increases the toxicity of lipopolysaccharides.

Authors:  J S Cowdery; J H Chace; A K Yi; A M Krieg
Journal:  J Immunol       Date:  1996-06-15       Impact factor: 5.422

9.  T cell growth and differentiation induced by interleukin-HP1/IL-6, the murine hybridoma/plasmacytoma growth factor.

Authors:  C Uyttenhove; P G Coulie; J Van Snick
Journal:  J Exp Med       Date:  1988-04-01       Impact factor: 14.307

10.  Type I interferon-mediated stimulation of T cells by CpG DNA.

Authors:  S Sun; X Zhang; D F Tough; J Sprent
Journal:  J Exp Med       Date:  1998-12-21       Impact factor: 14.307

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  8 in total

1.  Use of immunostimulatory sequence-containing oligonucleotides as topical therapy for genital herpes simplex virus type 2 infection.

Authors:  Richard B Pyles; Debbie Higgins; Claudia Chalk; Anthony Zalar; Joseph Eiden; Carrie Brown; Gary Van Nest; Lawrence R Stanberry
Journal:  J Virol       Date:  2002-11       Impact factor: 5.103

2.  Liposome-encapsulated CpG enhances antitumor activity accompanying the changing of lymphocyte populations in tumor via intratumoral administration.

Authors:  Dong Hyeok Kim; Chaerin Moon; Sang-Seok Oh; Soojong Park; Jin-Woo Jeong; Suk Kim; Hee Gu Lee; Hyung-Joo Kwon; Kwang Dong Kim
Journal:  Nucleic Acid Ther       Date:  2015-02-18       Impact factor: 5.486

3.  Divergent synthetic nucleotide motif recognition pattern: design and development of potent immunomodulatory oligodeoxyribonucleotide agents with distinct cytokine induction profiles.

Authors:  Ekambar R Kandimalla; Lakshmi Bhagat; Daqing Wang; Dong Yu; Fu-Gang Zhu; Jimmy Tang; Hui Wang; Ping Huang; Ruiwen Zhang; Sudhir Agrawal
Journal:  Nucleic Acids Res       Date:  2003-05-01       Impact factor: 16.971

4.  Coinjection with CpG-containing immunostimulatory oligodeoxynucleotides reduces the pathogenicity of a live vaccine against cutaneous Leishmaniasis but maintains its potency and durability.

Authors:  Susana Mendez; Khaled Tabbara; Yasmine Belkaid; Sylvie Bertholet; Daniela Verthelyi; Dennis Klinman; Robert A Seder; David L Sacks
Journal:  Infect Immun       Date:  2003-09       Impact factor: 3.441

5.  Superior protective immunity against murine listeriosis by combined vaccination with CpG DNA and recombinant Salmonella enterica serovar typhimurium.

Authors:  Christina Berchtold; Klaus Panthel; Stefan Jellbauer; Brigitte Köhn; Elisabeth Roider; Miriam Partilla; Jürgen Heesemann; Stefan Endres; Carole Bourquin; Holger Rüssmann
Journal:  Infect Immun       Date:  2009-09-21       Impact factor: 3.441

6.  Adjuvants for Leishmania vaccines: from models to clinical application.

Authors:  Vanitha S Raman; Malcolm S Duthie; Christopher B Fox; Greg Matlashewski; Steven G Reed
Journal:  Front Immunol       Date:  2012-06-11       Impact factor: 7.561

7.  Effects of skeletal unloading on the antibody repertoire of tetanus toxoid and/or CpG treated C57BL/6J mice.

Authors:  Trisha A Rettig; Bailey A Bye; Nina C Nishiyama; Savannah Hlavacek; Claire Ward; Michael J Pecaut; Stephen K Chapes
Journal:  PLoS One       Date:  2019-01-17       Impact factor: 3.240

8.  Vaccination with L. infantum chagasi nucleosomal histones confers protection against new world cutaneous leishmaniasis caused by Leishmania braziliensis.

Authors:  Marcia W Carneiro; Diego M Santos; Kiyoshi F Fukutani; Jorge Clarencio; Jose Carlos Miranda; Claudia Brodskyn; Aldina Barral; Manoel Barral-Netto; Manuel Soto; Camila I de Oliveira
Journal:  PLoS One       Date:  2012-12-20       Impact factor: 3.240

  8 in total

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