Literature DB >> 21257305

Economic evaluation of four follow-up strategies after curative treatment for breast cancer: results of an RCT.

M L Kimman1, C D Dirksen, A C Voogd, P Falger, B C M Gijsen, M Thuring, A Lenssen, F van der Ent, J Verkeyn, C Haekens, P Hupperets, J K S Nuytinck, Y van Riet, S J Brenninkmeijer, L J E E Scheijmans, A Kessels, Ph Lambin, L J Boersma.   

Abstract

BACKGROUND: An economic evaluation was performed alongside a randomised controlled trial (ISRCTN 74071417) investigating the cost-effectiveness of nurse-led telephone follow-up instead of hospital visits, and of a short educational group programme (EGP) in the first year after breast cancer treatment.
METHOD: This economic evaluation (n = 299) compared the one-year costs and the effects of four follow-up strategies: (1) hospital follow-up; (2) nurse-led telephone follow-up; (3) hospital follow-up plus EGP; and (4) nurse-led telephone follow-up plus EGP. Costs were measured using cost diaries and hospital registrations. Quality-adjusted life years (QALYs) were measured using the EQ-5D. Outcomes were expressed in incremental cost-effectiveness ratios (ICERs) and cost-effectiveness acceptability curves.
RESULTS: Hospital follow-up plus EGP yielded most QALYs (0.776), but also incurred the highest mean annual costs (€4914). The ICER of this strategy versus the next best alternative, nurse-led telephone follow-up plus EGP (0.772 QALYs and €3971), amounted to €235.750/QALY. Hospital and telephone follow-up without EGP both incurred higher costs and less QALYs than telephone follow-up plus EGP and were judged inferior. Hospital follow-up plus EGP was not considered cost-effective, therefore, telephone follow-up plus EGP was the preferred strategy. The probability of telephone follow-up plus EGP being cost-effective ranged from 49% to 62% for different QALY threshold values. Secondary and sensitivity analyses showed that results were robust.
CONCLUSION: Nurse-led telephone follow-up plus EGP seems an appropriate and cost-effective alternative to hospital follow-up for breast cancer patients during their first year after treatment.
Copyright © 2010 Elsevier Ltd. All rights reserved.

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Year:  2011        PMID: 21257305     DOI: 10.1016/j.ejca.2010.12.017

Source DB:  PubMed          Journal:  Eur J Cancer        ISSN: 0959-8049            Impact factor:   9.162


  24 in total

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7.  Empirical analysis shows reduced cost data collection may be an efficient method in economic clinical trials.

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9.  Follow-up strategies following completion of primary cancer treatment in adult cancer survivors.

Authors:  Beverley L Høeg; Pernille E Bidstrup; Randi V Karlsen; Anne Sofie Friberg; Vanna Albieri; Susanne O Dalton; Lena Saltbæk; Klaus Kaae Andersen; Trine Allerslev Horsboel; Christoffer Johansen
Journal:  Cochrane Database Syst Rev       Date:  2019-11-21

Review 10.  Telehealth Interventions Designed for Women: an Evidence Map.

Authors:  Karen M Goldstein; Leah L Zullig; Eric A Dedert; Amir Alishahi Tabriz; Timothy W Brearly; Giselle Raitz; Suchita Shah Sata; John D Whited; Hayden B Bosworth; Adelaide M Gordon; Avishek Nagi; John W Williams; Jennifer M Gierisch
Journal:  J Gen Intern Med       Date:  2018-10-03       Impact factor: 6.473

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