Literature DB >> 21254287

Enhanced physician adherence to antibiotic use guidelines through increased availability of guidelines at the time of drug ordering in hospital setting.

Jean-Frederic Westphal1, Francois Jehl, Herve Javelot, Cathy Nonnenmacher.   

Abstract

PURPOSE: Some studies have shown that making practice guidelines accessible to physicians when they are making clinical decisions could improve prescribing practices. The aim of the study was to assess the benefit of impact on physician adherence of the intervention that consisted of embedding previously paper-based antibiotic guidelines in the computerized physician drug order entry system of a teaching hospital in order to make these guidelines available to physician at the time of antibiotic ordering. Before the intervention, these guidelines were available in booklet form in all the wards of the hospital.
METHODS: Adherence to guidelines was evaluated in 471 consecutive antibiotic orders for pneumonia, 104 just before and 367 just after the intervention. The evaluation criteria were: the choice of the antibiotic relative to the context of acquisition of pneumonia, the daily dose, the planned duration of treatment. Evaluation of antibiotic orders was performed at the initiation of antibiotic treatment.
RESULTS: The intervention was followed by a significant decrease in the proportion of antibiotic orders containing at least one criterion of non-conformity to the guidelines, respectively, 33% after vs. 51% (p<0.001) before the intervention. Proportion of non-conform orders decreased in the post- vs. pre-intervention period for the daily dosage of antibiotics, respectively, 12.2% vs. 26.9% (p<0.001), for the planned duration of treatment, respectively, 7.3% vs. 18.3% (p<0.001), whereas for the choice of antibiotics relative to the context of acquisition of pneumonia, the improvement failed to reach statistical significance, respectively, 18.2% vs. 25% (p=0.12).
CONCLUSION: In this study, the increased availability of antibiotic guidelines at the time of drug ordering, combined with a periodical reinforcement educational round, was associated with an enhanced physician adherence to these guidelines.
Copyright © 2010 John Wiley & Sons, Ltd.

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Year:  2010        PMID: 21254287     DOI: 10.1002/pds.2078

Source DB:  PubMed          Journal:  Pharmacoepidemiol Drug Saf        ISSN: 1053-8569            Impact factor:   2.890


  10 in total

1.  Evaluating incorporation of drug restrictions into computerized drug order entries after transition to an electronic health record.

Authors:  Ryan Rodriguez; Benjamin Staley; Randy C Hatton
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2.  Strategies to enhance rational use of antibiotics in hospital: a guideline by the German Society for Infectious Diseases.

Authors:  K de With; F Allerberger; S Amann; P Apfalter; H-R Brodt; T Eckmanns; M Fellhauer; H K Geiss; O Janata; R Krause; S Lemmen; E Meyer; H Mittermayer; U Porsche; E Presterl; S Reuter; B Sinha; R Strauß; A Wechsler-Fördös; C Wenisch; W V Kern
Journal:  Infection       Date:  2016-06       Impact factor: 3.553

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Journal:  Eur J Hosp Pharm       Date:  2018-11-26

Review 4.  Educational interventions to improve prescription and dispensing of antibiotics: a systematic review.

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6.  A single center observational study on emergency department clinician non-adherence to clinical practice guidelines for treatment of uncomplicated urinary tract infections.

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7.  Monitoring adherence to guidelines of antibiotic use in pediatric pneumonia: the MAREA study.

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Review 8.  The effectiveness of computerised decision support on antibiotic use in hospitals: A systematic review.

Authors:  Christopher E Curtis; Fares Al Bahar; John F Marriott
Journal:  PLoS One       Date:  2017-08-24       Impact factor: 3.240

9.  Retrospective Analysis of Drug Prescription Statistics in a Tertiary Care Center in India: Recommendations for Promoting Prudent Utilization of Drugs.

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Journal:  J Res Pharm Pract       Date:  2020-10-08

10.  Drug utilisation study in a tertiary care center: recommendations for improving hospital drug dispensing policies.

Authors:  Niti Mittal; R Mittal; I Singh; Nusrat Shafiq; S Malhotra
Journal:  Indian J Pharm Sci       Date:  2014-07       Impact factor: 0.975

  10 in total

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