Literature DB >> 21253634

An electrochemical approach for detection of DNA methylation and assay of the methyltransferase activity.

Shuna Liu1, Ping Wu, Wen Li, Hui Zhang, Chenxin Cai.   

Abstract

This work develops an electrochemical approach for rapid detection of the genomic DNA methylation level, assay of methyltransferase activity, and evaluation and screening of the inhibitors of methyltransferase. This method may be a help for the discovery of anticancer drugs.

Mesh：

Substances：

Year:  2011        PMID： 21253634     DOI： 10.1039/c0cc05153e

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  5 in total

1.  Probing for DNA methylation with a voltammetric DNA detector.

Authors:  Amir Saheb; Stephanie Patterson; Mira Josowicz
Journal:  Analyst       Date:  2014-02-21       Impact factor: 4.616

2.  Electrochemical direct detection of DNA deamination catalyzed by APOBEC3G.

Authors:  Junya Chiba; Takahide Kouno; Shun Aoki; Hitoshi Sato; JingYing Zhang; Hiroshi Matsuo; Masahiko Inouye
Journal:  Chem Commun (Camb)       Date:  2012-11-12       Impact factor: 6.222

3.  Label-free electrochemical detection of human methyltransferase from tumors.

Authors:  Ariel L Furst; Natalie B Muren; Michael G Hill; Jacqueline K Barton
Journal:  Proc Natl Acad Sci U S A       Date:  2014-10-06       Impact factor: 11.205

4.  Electrochemical assay for the signal-on detection of human DNA methyltransferase activity.

Authors:  Natalie B Muren; Jacqueline K Barton
Journal:  J Am Chem Soc       Date:  2013-11-06       Impact factor: 15.419

Review 5.  DNA Methyltransferase Activity Assays: Advances and Challenges.

Authors:  Wan Jun Poh; Cayden Pang Pee Wee; Zhiqiang Gao
Journal:  Theranostics       Date:  2016-01-06       Impact factor: 11.556
  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.