Shama Munim1, Fauzia Haq Nawaz, Salma Ayub. 1. Department of Obstetrics and Gynecology, P.O. Box 3500, Karachi, 74800, Pakistan. shama.munim@aku.edu
Abstract
OBJECTIVES: To examine the possible etiological causes of still births during 8 years of clinical experience at a tertiary referral center, The Aga Khan University Hospital Karachi Pakistan. In addition, to compare demographic and medical risk factors along with analysis of cause of fetal death in different groups. MATERIAL AND METHODS: This was a retrospective cohort study, conducted at the Aga Khan University Karachi, Pakistan over a period of 8-year period between January 2000 and January 2008. We reviewed 287 medical records of all women who had intrauterine fetal demise during study time period. RESULTS: The prevalence of still births at our institution was 6.6 +/- 2.1 per 1000 total births. Congenital anomalies, maternal hypertension, and fetal growth restrictions were the three main causes of still births. About half of still births were among unbooked pregnant women. More than 90% of occurred during the ante natal period while 10% were intrapartum. Majority of stillborns were in macerated state when delivered. CONCLUSION: Most of still births were due to known causes such as hypertension, congenital anomalies, and fetal growth restriction. Improvement in the management of hypertension and diagnosis of congenital anomalies is necessary. Results of the analysis urge on the need for antenatal care and compliance for follow-ups.
OBJECTIVES: To examine the possible etiological causes of still births during 8 years of clinical experience at a tertiary referral center, The Aga Khan University Hospital Karachi Pakistan. In addition, to compare demographic and medical risk factors along with analysis of cause of fetal death in different groups. MATERIAL AND METHODS: This was a retrospective cohort study, conducted at the Aga Khan University Karachi, Pakistan over a period of 8-year period between January 2000 and January 2008. We reviewed 287 medical records of all women who had intrauterine fetal demise during study time period. RESULTS: The prevalence of still births at our institution was 6.6 +/- 2.1 per 1000 total births. Congenital anomalies, maternal hypertension, and fetal growth restrictions were the three main causes of still births. About half of still births were among unbooked pregnant women. More than 90% of occurred during the ante natal period while 10% were intrapartum. Majority of stillborns were in macerated state when delivered. CONCLUSION: Most of still births were due to known causes such as hypertension, congenital anomalies, and fetal growth restriction. Improvement in the management of hypertension and diagnosis of congenital anomalies is necessary. Results of the analysis urge on the need for antenatal care and compliance for follow-ups.
Authors: Stephen H Kennedy; Cesar G Victora; Ricardo Uauy; Zulfiqar A Bhutta; José Villar; Rachel Craik; Stephen Ash; Fernando C Barros; Hellen C Barsosio; James A Berkley; Maria Carvalho; Michelle Fernandes; Leila Cheikh Ismail; Ann Lambert; Cecilia M Lindgren; Rose McGready; Shama Munim; Christoffer Nellåker; Julia A Noble; Shane A Norris; Francois Nosten; Eric O Ohuma; Aris T Papageorghiou; Alan Stein; William Stones; Chrystelle O O Tshivuila-Matala; Eleonora Staines Urias; Manu Vatish; Katharina Wulff; Ghulam Zainab; Krina T Zondervan Journal: Gates Open Res Date: 2019-02-05