Literature DB >> 21247476

Squamous cell carcinoma of the tonsillar remnant--clinical presentation and oncological outcome.

Christopher J Skilbeck1, Jean-Pierre Jeannon, Mary O'Connell, Peter R Morgan, Ricard Simo.   

Abstract

BACKGROUND: Squamous cell carcinoma (SCC) of the tonsil is the most common malignant tumour of the oropharynx. Paediatric tonsillectomy is one of the most commonly performed procedures in Otorhinolaryngology. SCC of the tonsil remnant (SCCTR) in a previously tonsillectomised patient is rare.
METHODS: Retrospective review of patients with SCCTR presenting to the Otorhinolaryngology, Head and Neck Unit January 2000 to December 2007.
RESULTS: Two hundred and fifty patients with tonsil SCC were identified. Ten (4%) of these had previously undergone tonsillectomy in childhood. Nine patients underwent radical treatment including surgery, radiotherapy and in four cases concomitant chemotherapy. Eight patients are alive with no signs of recurrence with follow-up of a minimum of 24 months. One has been lost from follow-up.
CONCLUSIONS: Clinicians should be aware that SCC can arise from a tonsillar remnant. SCCTR has similar oncological outcomes as tonsillar tumours.

Entities:  

Mesh:

Year:  2011        PMID: 21247476      PMCID: PMC3038984          DOI: 10.1186/1758-3284-3-4

Source DB:  PubMed          Journal:  Head Neck Oncol        ISSN: 1758-3284


  14 in total

Review 1.  Controlling advanced neck disease: efficacy of neck dissection and radiotherapy.

Authors:  B L Richards; J D Spiro
Journal:  Laryngoscope       Date:  2000-07       Impact factor: 3.325

2.  CUP (carcinoma of unknown primary) syndrome in head and neck: clinic, diagnostic, and therapy.

Authors:  A Weber; S Schmoz; F Bootz
Journal:  Onkologie       Date:  2001-02

Review 3.  Synchronous bilateral tonsillar carcinoma: role of fluoro-deoxyglucose positron emission tomography scanning in detecting occult primary tumours in metastatic nodal disease of the head and neck.

Authors:  T Price; J Pickles
Journal:  J Laryngol Otol       Date:  2006-04       Impact factor: 1.469

4.  Squamous cell carcinoma metastatic to the neck from an unknown head and neck primary site.

Authors:  W M Mendenhall; A A Mancuso; R J Amdur; S P Stringer; D B Villaret; N J Cassisi
Journal:  Am J Otolaryngol       Date:  2001 Jul-Aug       Impact factor: 1.808

5.  Tonsillotomy or tonsillectomy?--a prospective study comparing histological and immunological findings in recurrent tonsillitis and tonsillar hyperplasia.

Authors:  Oliver Reichel; Doris Mayr; Jan Winterhoff; Richard de la Chaux; Hjalmar Hagedorn; Alexander Berghaus
Journal:  Eur Arch Otorhinolaryngol       Date:  2006-09-21       Impact factor: 2.503

6.  Screening unilateral tonsillectomy in the unknown primary.

Authors:  P D Righi; R A Sofferman
Journal:  Laryngoscope       Date:  1995-05       Impact factor: 3.325

7.  Cancer of the tonsil: the results of ipsilateral radiation treatment.

Authors:  S M Jackson; J H Hay; A D Flores; L Weir; F L Wong; C Schwindt; B Baerg
Journal:  Radiother Oncol       Date:  1999-05       Impact factor: 6.280

8.  Squamous carcinoma presenting as an enlarged cervical lymph node.

Authors:  A S Jones; J A Cook; D E Phillips; N R Roland
Journal:  Cancer       Date:  1993-09-01       Impact factor: 6.860

Review 9.  Metastatic squamous cell carcinoma of occult primary: beware the tonsillar remnant.

Authors:  R Simo; M O'Connell
Journal:  J Laryngol Otol       Date:  2007-06-11       Impact factor: 1.469

10.  The impact of FDG PET on the management of occult primary head and neck tumours.

Authors:  W L Wong; M Saunders
Journal:  Clin Oncol (R Coll Radiol)       Date:  2003-12       Impact factor: 4.126

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  1 in total

Review 1.  Synchronous tonsillar tumors with differing histopathology: A case report and review of the literature.

Authors:  Nicholas A Rossi; Devin N Reddy; Jordan W Rawl; Jianli Dong; Suimin Qiu; Cecilia G Clement; Vicente A Resto; Rohan Joshi; Brian McKinnon; Orly Coblens
Journal:  Cancer Rep (Hoboken)       Date:  2022-03-14
  1 in total

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