Literature DB >> 21245478

Associations of hip osteoarthritis with history of recurrent exposure to manual handling of loads over 20 kg and work participation: a population-based study of men and women.

Leena Kaila-Kangas1, Jari Arokoski, Olli Impivaara, Eira Viikari-Juntura, Päivi Leino-Arjas, Ritva Luukkonen, Markku Heliövaara.   

Abstract

OBJECTIVES: We reviewed work histories of manual handling of loads >20 kg in relation to hip osteoarthritis by age, exposure and work participation.
METHODS: A nationally representative sample of 3110 Finnish men and 3446 women aged 30-97 was recruited. Diagnosis of hip osteoarthritis was based on standardised clinical examination by trained physicians. Previous exposure to physically loading work was evaluated through interviews. Logistic regression was used to estimate associations between work factors and hip osteoarthritis.
RESULTS: 1.9% of men and 2.1% of women had hip osteoarthritis. Almost half the men and a quarter of the women had recurrently handled heavy loads at work. Subjects who had manually handled loads >20 kg had a 1.8-fold increased risk of hip osteoarthritis compared to non-exposed references, when age, body mass index, traumatic fractures and smoking were accounted for. Results were similar for men (OR 2.0; 95% CI 1.0 to 4.0) and women (1.8; 1.1 to 2.8). In a sub-analysis of subjects with hip replacement, the OR was 1.7 (1.0 to 2.9). Risk increased first after 12 years' exposure: among men it was 2.2 (0.8 to 5.9) for 13-24 years' exposure, and 2.3 (1.2 to 4.3) for >24 years' exposure. Among women it was 3.8 (1.7 to 8.1) for 13-24 years' exposure. Work participation among men aged <60 years with hip osteoarthritis was 20% lower compared with subjects without osteoarthritis.
CONCLUSIONS: A work history of manual handling of loads >20 kg showed a strong association with hip osteoarthritis in all age groups except the youngest.

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Year:  2011        PMID: 21245478     DOI: 10.1136/oem.2010.061390

Source DB:  PubMed          Journal:  Occup Environ Med        ISSN: 1351-0711            Impact factor:   4.402


  15 in total

1.  In vivo cyclic compression causes cartilage degeneration and subchondral bone changes in mouse tibiae.

Authors:  Frank C Ko; Cecilia Dragomir; Darren A Plumb; Steven R Goldring; Timothy M Wright; Mary B Goldring; Marjolein C H van der Meulen
Journal:  Arthritis Rheum       Date:  2013-06

2.  Mechanobiological Mechanisms of Load-Induced Osteoarthritis in the Mouse Knee.

Authors:  Olufunmilayo O Adebayo; Derek T Holyoak; Marjolein C H van der Meulen
Journal:  J Biomech Eng       Date:  2019-07-01       Impact factor: 2.097

Review 3.  Occupational and genetic risk factors for osteoarthritis: a review.

Authors:  Berran Yucesoy; Luenda E Charles; Brent Baker; Cecil M Burchfiel
Journal:  Work       Date:  2015-01-01

4.  Kinematics of meniscal- and ACL-transected mouse knees during controlled tibial compressive loading captured using roentgen stereophotogrammetry.

Authors:  Olufunmilayo O Adebayo; Frank C Ko; Steven R Goldring; Mary B Goldring; Timothy M Wright; Marjolein C H van der Meulen
Journal:  J Orthop Res       Date:  2016-10-03       Impact factor: 3.494

5.  Occupational Strain as a Risk for Hip Osteoarthritis.

Authors:  Annekatrin Bergmann; Ulrich Bolm-Audorff; Daniel Krone; Andreas Seidler; Falk Liebers; Johannes Haerting; Alice Freiberg; Susanne Unverzagt
Journal:  Dtsch Arztebl Int       Date:  2017-09-04       Impact factor: 5.594

6.  Progressive cell-mediated changes in articular cartilage and bone in mice are initiated by a single session of controlled cyclic compressive loading.

Authors:  Frank C Ko; Cecilia L Dragomir; Darren A Plumb; Allison W Hsia; Olufunmilayo O Adebayo; Steven R Goldring; Timothy M Wright; Mary B Goldring; Marjolein C H van der Meulen
Journal:  J Orthop Res       Date:  2016-03-21       Impact factor: 3.494

7.  An expert-based job exposure matrix for large scale epidemiologic studies of primary hip and knee osteoarthritis: the Lower Body JEM.

Authors:  Tine Steen Rubak; Susanne Wulff Svendsen; Johan Hviid Andersen; Jens Peder Lind Haahr; Ann Kryger; Lone Donbæk Jensen; Poul Frost
Journal:  BMC Musculoskelet Disord       Date:  2014-06-13       Impact factor: 2.362

8.  Dose-response relationship between cumulative physical workload and osteoarthritis of the hip - a meta-analysis applying an external reference population for exposure assignment.

Authors:  Andreas Seidler; Laura Lüben; Janice Hegewald; Ulrich Bolm-Audorff; Annekatrin Bergmann; Falk Liebers; Christina Ramdohr; Karla Romero Starke; Alice Freiberg; Susanne Unverzagt
Journal:  BMC Musculoskelet Disord       Date:  2018-06-01       Impact factor: 2.362

Review 9.  HIP osteoarthritis and work.

Authors:  E Clare Harris; David Coggon
Journal:  Best Pract Res Clin Rheumatol       Date:  2015-06-10       Impact factor: 4.098

10.  Hip Osteoarthritis and Physical Workload: Influence of Study Quality on Risk Estimations-A Meta-Analysis of Epidemiological Findings.

Authors:  Yi Sun; Annette Nold; Ulrich Glitsch; Frank Bochmann
Journal:  Int J Environ Res Public Health       Date:  2019-01-24       Impact factor: 3.390

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