Literature DB >> 2123475

A new Igk-V gene family in the mouse.

N M Valiante1, A J Caton.   

Abstract

We have identified and characterized a novel mouse Igk-V gene family, which we have designated Igk-V34. Southern hybridization and nucleotide sequence analysis indicate that this family is comprised of either one or two members in mice of different Igk haplotypes. The gene family members share between 95% and 98% sequence similarity, indicating that they diverged only recently during the evolution of the Igk locus. Sequence relationships between members of this family are discussed.

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Year:  1990        PMID： 2123475     DOI： 10.1007/bf00211649

Source DB:  PubMed          Journal:  Immunogenetics        ISSN： 0093-7711            Impact factor:   2.846


  15 in total

1.  Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase.

Authors:  R K Saiki; D H Gelfand; S Stoffel; S J Scharf; R Higuchi; G T Horn; K B Mullis; H A Erlich
Journal:  Science       Date:  1988-01-29       Impact factor: 47.728

Review 2.  Gene conversion and the generation of antibody diversity.

Authors:  L J Wysocki; M L Gefter
Journal:  Annu Rev Biochem       Date:  1989       Impact factor: 23.643

Review 3.  Somatic generation of antibody diversity.

Authors:  S Tonegawa
Journal:  Nature       Date:  1983-04-14       Impact factor: 49.962

4.  Functional and non-functional joining in immunoglobulin light chain genes of a mouse myeloma.

Authors:  W Altenburger; M Steinmetz; H G Zachau
Journal:  Nature       Date:  1980-10-16       Impact factor: 49.962

5.  Classification of mouse VK groups based on the partial amino acid sequence to the first invariant tryptophan: impact of 14 new sequences from IgG myeloma proteins.

Authors:  M Potter; J B Newell; S Rudikoff; E Haber
Journal:  Mol Immunol       Date:  1982-12       Impact factor: 4.407

6.  The immunoglobulin heavy chain variable region (Igh-V) locus in the mouse. I. One hundred Igh-V genes comprise seven families of homologous genes.

Authors:  P H Brodeur; R Riblet
Journal:  Eur J Immunol       Date:  1984-10       Impact factor: 5.532

7.  Organization of the murine immunoglobulin VH complex in the inbred strains.

Authors:  G A Rathbun; J D Capra; P W Tucker
Journal:  EMBO J       Date:  1987-10       Impact factor: 11.598

8.  Structural and functional implications of a restricted antibody response to a defined antigenic region on the influenza virus hemagglutinin.

Authors:  A J Caton; G G Brownlee; L M Staudt; W Gerhard
Journal:  EMBO J       Date:  1986-07       Impact factor: 11.598

9.  Anti-DNA antibodies from autoimmune mice arise by clonal expansion and somatic mutation.

Authors:  M Shlomchik; M Mascelli; H Shan; M Z Radic; D Pisetsky; A Marshak-Rothstein; M Weigert
Journal:  J Exp Med       Date:  1990-01-01       Impact factor: 14.307

10.  Generation of antibody diversity in the immune response of BALB/c mice to influenza virus hemagglutinin. I. Significant variation in repertoire expression between individual mice.

Authors:  L M Staudt; W Gerhard
Journal:  J Exp Med       Date:  1983-02-01       Impact factor: 14.307
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  4 in total

1.  A new Igk-V gene family in the mouse.

Authors:  R Kofler; A Helmberg
Journal:  Immunogenetics       Date:  1991       Impact factor: 2.846

2.  Rapid cloning of any rearranged mouse immunoglobulin variable genes.

Authors:  A K Dattamajumdar; D P Jacobson; L E Hood; G E Osman
Journal:  Immunogenetics       Date:  1996       Impact factor: 2.846

3.  Yeast artificial chromosome contigs reveal that distal variable-region genes reside at least 3 megabases from the joining regions in the murine immunoglobulin kappa locus.

Authors:  J B George; S Li; W T Garrard
Journal:  Proc Natl Acad Sci U S A       Date:  1995-12-19       Impact factor: 11.205

4.  Restricted immunoglobulin variable region (Ig V) gene expression accompanies secondary rearrangements of light chain Ig V genes in mouse plasmacytomas.

Authors:  L Diaw; D Siwarski; A Coleman; J Kim; G M Jones; G Dighiero; K Huppi
Journal:  J Exp Med       Date:  1999-11-15       Impact factor: 14.307
  4 in total

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