Literature DB >> 21229178

Localization of antimicrobial peptides on polymerized liposomes leading to their enhanced efficacy against Pseudomonas aeruginosa.

Amit Kumar1, Satya S Kolar, Meriong Zao, Alison M McDermott, Chengzhi Cai.   

Abstract

Antimicrobial peptide IG-25 (a truncated version of LL-37 of the cathelicidin family) tethering an azido-capped poly(ethylene glycol) chain at the N-terminus was site-specifically attached to alkynyl-terminated polymerized liposomes using copper catalyzed "click" reaction, leading to an 18 fold enhancement in efficacy against Pseudomonas aeruginosa when compared to LL-37 without any increase in cytotoxicity to human corneal epithelial cells.

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Year:  2011        PMID： 21229178      PMCID： PMC3235330          DOI： 10.1039/c0mb00207k

Source DB:  PubMed          Journal:  Mol Biosyst        ISSN： 1742-2051


  43 in total

1.  Antimicrobial dendrimeric peptides.

Authors:  James P Tam; Yi-An Lu; Jin-Long Yang
Journal:  Eur J Biochem       Date:  2002-02

2.  Antifungal coating by biofunctionalized polyelectrolyte multilayered films.

Authors:  Olivier Etienne; Claire Gasnier; Corinne Taddei; Jean-Claude Voegel; Dominique Aunis; Pierre Schaaf; Marie-Helène Metz-Boutigue; Anne-Laure Bolcato-Bellemin; Christophe Egles
Journal:  Biomaterials       Date:  2005-11       Impact factor: 12.479

3.  Enhanced membrane pore formation by multimeric/oligomeric antimicrobial peptides.

Authors:  Christopher J Arnusch; Hilbert Branderhorst; Ben de Kruijff; Rob M J Liskamp; Eefjan Breukink; Roland J Pieters
Journal:  Biochemistry       Date:  2007-10-18       Impact factor: 3.162

Review 4.  Electrically gated ionic channels in lipid bilayers.

Authors:  G Ehrenstein; H Lecar
Journal:  Q Rev Biophys       Date:  1977-02       Impact factor: 5.318

5.  "Clickable", polymerized liposomes as a versatile and stable platform for rapid optimization of their peripheral compositions.

Authors:  Amit Kumar; Uriel J Erasquin; Guoting Qin; King Li; Chengzhi Cai
Journal:  Chem Commun (Camb)       Date:  2010-06-28       Impact factor: 6.222

6.  Preparation of LL-37-grafted titanium surfaces with bactericidal activity.

Authors:  Matthias Gabriel; Kamran Nazmi; Enno C Veerman; Arie V Nieuw Amerongen; Andrej Zentner
Journal:  Bioconjug Chem       Date:  2006 Mar-Apr       Impact factor: 4.774

7.  A novel cationic-peptide coating for the prevention of microbial colonization on contact lenses.

Authors:  M D P Willcox; E B H Hume; Y Aliwarga; N Kumar; N Cole
Journal:  J Appl Microbiol       Date:  2008-11-01       Impact factor: 3.772

8.  Antibacterial and antifouling polymer brushes incorporating antimicrobial peptide.

Authors:  Karine Glinel; Alain M Jonas; Thierry Jouenne; Jérôme Leprince; Ludovic Galas; Wilhelm T S Huck
Journal:  Bioconjug Chem       Date:  2009-01       Impact factor: 4.774

9.  The efficacy of self-assembled cationic antimicrobial peptide nanoparticles against Cryptococcus neoformans for the treatment of meningitis.

Authors:  Huaying Wang; Kaijin Xu; Lihong Liu; Jeremy P K Tan; Yunbo Chen; Yongtao Li; Weimin Fan; Zeqing Wei; Jifang Sheng; Yi-Yan Yang; Lanjuan Li
Journal:  Biomaterials       Date:  2009-12-31       Impact factor: 12.479

Review 10.  A toxicologic review of quantum dots: toxicity depends on physicochemical and environmental factors.

Authors:  Ron Hardman
Journal:  Environ Health Perspect       Date:  2006-02       Impact factor: 9.031
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  4 in total

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Authors:  Satya S Kolar; Alison M McDermott
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Review 2.  Antimicrobial Peptide Expression at the Ocular Surface and Their Therapeutic Use in the Treatment of Microbial Keratitis.

Authors:  Allison H Shannon; Sara A Adelman; Erin A Hisey; Sanskruti S Potnis; Vanessa Rozo; Madeline W Yung; Jennifer Y Li; Christopher J Murphy; Sara M Thomasy; Brian C Leonard
Journal:  Front Microbiol       Date:  2022-06-02       Impact factor: 6.064

3.  Esculentin-1a(1-21)NH2: a frog skin-derived peptide for microbial keratitis.

Authors:  Satya Sree N Kolar; Vincenzo Luca; Hasna Baidouri; Giuseppe Mannino; Alison M McDermott; Maria Luisa Mangoni
Journal:  Cell Mol Life Sci       Date:  2014-08-03       Impact factor: 9.261

Review 4.  Mitochondrion: A Promising Target for Nanoparticle-Based Vaccine Delivery Systems.

Authors:  Ru Wen; Afoma C Umeano; Lily Francis; Nivita Sharma; Smanla Tundup; Shanta Dhar
Journal:  Vaccines (Basel)       Date:  2016-06-01
  4 in total

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