AIMS: The purpose of the study was to examine the relationship between the initial cycle length (CL) of ventricular tachycardia (VT) and the size of the myocardial scar and its border zone in patients with old myocardial infarction (MI). METHODS AND RESULTS: Late gadolinium-enhancement cardiac magnetic resonance was performed prior to implantable cardioverter-defibrillator (ICD) implantation in 24 patients. The size of non-scared myocardium, scar, scar core, and border zone were measured as voxel numbers. The number of core islands, contour-regularity of scar and left-ventricular ejection fraction were also calculated. During the first year after ICD implantation, VT was recorded in 20 patients. With univariate regression analysis, the number of core islands had the highest correlation with the CL of VT (R = 0.614, adjusted R(2) = 0.342, P = 0.004). By multiple regression analyses, the highest correlation was found by the use of scar core and core islands (R = 0.721, adjusted R(2) = 0.464, P = 0.002). CONCLUSION: The heart rate of VT (bpm) in patients with old MI is inversely related to the properties of the densest parts of the myocardial scar.
AIMS: The purpose of the study was to examine the relationship between the initial cycle length (CL) of ventricular tachycardia (VT) and the size of the myocardial scar and its border zone in patients with old myocardial infarction (MI). METHODS AND RESULTS: Late gadolinium-enhancement cardiac magnetic resonance was performed prior to implantable cardioverter-defibrillator (ICD) implantation in 24 patients. The size of non-scared myocardium, scar, scar core, and border zone were measured as voxel numbers. The number of core islands, contour-regularity of scar and left-ventricular ejection fraction were also calculated. During the first year after ICD implantation, VT was recorded in 20 patients. With univariate regression analysis, the number of core islands had the highest correlation with the CL of VT (R = 0.614, adjusted R(2) = 0.342, P = 0.004). By multiple regression analyses, the highest correlation was found by the use of scar core and core islands (R = 0.721, adjusted R(2) = 0.464, P = 0.002). CONCLUSION: The heart rate of VT (bpm) in patients with old MI is inversely related to the properties of the densest parts of the myocardial scar.
Authors: Daniel G León; Mariña López-Yunta; José Manuel Alfonso-Almazán; Manuel Marina-Breysse; Jorge G Quintanilla; Javier Sánchez-González; Carlos Galán-Arriola; Francisco Castro-Núñez; Juan José González-Ferrer; Borja Ibáñez; Julián Pérez-Villacastín; Nicasio Pérez-Castellano; Valentín Fuster; José Jalife; Mariano Vázquez; Jazmín Aguado-Sierra; David Filgueiras-Rama Journal: Europace Date: 2019-05-01 Impact factor: 5.214
Authors: Susana Merino-Caviedes; Lilian K Gutierrez; José Manuel Alfonso-Almazán; Santiago Sanz-Estébanez; Lucilio Cordero-Grande; Jorge G Quintanilla; Javier Sánchez-González; Manuel Marina-Breysse; Carlos Galán-Arriola; Daniel Enríquez-Vázquez; Carlos Torres; Gonzalo Pizarro; Borja Ibáñez; Rafael Peinado; Jose Luis Merino; Julián Pérez-Villacastín; José Jalife; Mariña López-Yunta; Mariano Vázquez; Jazmín Aguado-Sierra; Juan José González-Ferrer; Nicasio Pérez-Castellano; Marcos Martín-Fernández; Carlos Alberola-López; David Filgueiras-Rama Journal: Sci Rep Date: 2021-09-28 Impact factor: 4.379