| Literature DB >> 2122561 |
Abstract
Libraries of yeast artificial chromosomes (YACs) are representative of complex genomes, and typical YACs contain single fragments of DNA that are up to a megabase or more in size, are stable during growth, and are faithful to genomic DNA. Such YACs may permit (1) the use of complete gene units for a number of research and medical purposes; and (2) the assembly of chromosome-sized contigs in a single map that unifies genetic and physical data.Entities:
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Year: 1990 PMID: 2122561 DOI: 10.1016/0168-9525(90)90207-m
Source DB: PubMed Journal: Trends Genet ISSN: 0168-9525 Impact factor: 11.639