| Literature DB >> 21222464 |
Eric H Andrianasolo1, Liti Haramaty, Kerry L McPhail, Eileen White, Costantino Vetriani, Paul Falkowski, Richard Lutz.
Abstract
Two ceramide derivatives, bathymodiolamides A (1) and B (2), were isolated from the deep-sea hydrothermal vent invertebrate mussel Bathymodiolus thermophilus. The molecular structures of these compounds were determined using a combination of NMR spectroscopy, mass spectrometry, and chemical degradation. Biological activities were assessed in a ApopScreen cell-based screen for apoptosis induction and potential anticancer activity. To our knowledge, this is the first report of secondary metabolites from the marine hydrothermal vent mussel B. thermophilus.Entities:
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Year: 2011 PMID： 21222464 PMCID： PMC3081957 DOI： 10.1021/np100601w
Source DB: PubMed Journal: J Nat Prod ISSN： 0163-3864 Impact factor: 4.050