Nanotechnology and exposure science: what is needed to fill the research and data gaps for consumer products.

This article discusses the gaps in our understanding of human exposures to nanoparticles stemming from the use of nanotechnology-based consumer products by the general public. It also describes a series of steps that could be taken to characterize such exposures. The suggested steps include classification of the nanotechnology-based products, simulation of realistic exposure patterns, characterization of emissions, analysis of the duration of activities resulting in exposures, and consideration of the bioaccessibility of nanoparticles. In addition, we present a preliminary study with nanotechnology-based cosmetic powders where particle release was studied under realistic powder application conditions. The data demonstrated that when nanotechnology-based cosmetic powders were used, there was a potential for inhaling airborne particles ranging in size from tens of nanometers to tens of micrometers.