Literature DB >> 21221459

Purine 5',8-cyclonucleoside lesions: chemistry and biology.

Chryssostomos Chatgilialoglu1, Carla Ferreri, Michael A Terzidis.   

Abstract

5',8-Cyclo-2'-deoxyadenosine and 5',8-cyclo-2'-deoxyguanosine in their 5'R and 5'S diastereomeric forms are tandem-type lesions observed among the DNA modifications and identified in mammalian cellular DNA in vivo. These lesions result from the chemistry of the C5' radicals generated by the attack of HO˙ radicals to 2-deoxyribose units. Quantitative determination of these lesions in biological samples as biomarkers of free radical damage is a challenge. Results reported for irradiated samples of calf thymus DNA have been critically reviewed, underlining the need of further research for the potential involvement of these lesions in human health (76 references).

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Year:  2011        PMID： 21221459     DOI： 10.1039/c0cs00061b

Source DB:  PubMed          Journal:  Chem Soc Rev        ISSN： 0306-0012            Impact factor:   54.564


  48 in total

1.  Generation of guanine-thymidine cross-links in DNA by peroxynitrite/carbon dioxide.

Authors:  Byeong Hwa Yun; Nicholas E Geacintov; Vladimir Shafirovich
Journal:  Chem Res Toxicol       Date:  2011-05-04       Impact factor: 3.739

Review 2.  Biologically relevant oxidants and terminology, classification and nomenclature of oxidatively generated damage to nucleobases and 2-deoxyribose in nucleic acids.

Authors:  Jean Cadet; Steffen Loft; Ryszard Olinski; Mark D Evans; Karol Bialkowski; J Richard Wagner; Peter C Dedon; Peter Møller; Marc M Greenberg; Marcus S Cooke
Journal:  Free Radic Res       Date:  2012-02-22

Review 3.  Mass Spectrometry-Based Quantitative Strategies for Assessing the Biological Consequences and Repair of DNA Adducts.

Authors:  Changjun You; Yinsheng Wang
Journal:  Acc Chem Res       Date:  2016-01-13       Impact factor: 22.384

4.  The oxidative DNA lesions 8,5'-cyclopurines accumulate with aging in a tissue-specific manner.

Authors:  Jin Wang; Cheryl L Clauson; Paul D Robbins; Laura J Niedernhofer; Yinsheng Wang
Journal:  Aging Cell       Date:  2012-05-22       Impact factor: 9.304

Review 5.  Formation and repair of oxidatively generated damage in cellular DNA.

Authors:  Jean Cadet; Kelvin J A Davies; Marisa Hg Medeiros; Paolo Di Mascio; J Richard Wagner
Journal:  Free Radic Biol Med       Date:  2017-01-02       Impact factor: 7.376

Review 6.  Removal of oxidatively generated DNA damage by overlapping repair pathways.

Authors:  Vladimir Shafirovich; Nicholas E Geacintov
Journal:  Free Radic Biol Med       Date:  2016-11-04       Impact factor: 7.376

Review 7.  Occurrence, Biological Consequences, and Human Health Relevance of Oxidative Stress-Induced DNA Damage.

Authors:  Yang Yu; Yuxiang Cui; Laura J Niedernhofer; Yinsheng Wang
Journal:  Chem Res Toxicol       Date:  2016-11-07       Impact factor: 3.739

8.  The Nonbulky DNA Lesions Spiroiminodihydantoin and 5-Guanidinohydantoin Significantly Block Human RNA Polymerase II Elongation in Vitro.

Authors:  Marina Kolbanovskiy; Moinuddin A Chowdhury; Aditi Nadkarni; Suse Broyde; Nicholas E Geacintov; David A Scicchitano; Vladimir Shafirovich
Journal:  Biochemistry       Date:  2017-06-07       Impact factor: 3.162

9.  Generation of guanine-amino acid cross-links by a free radical combination mechanism.

Authors:  Yuriy Uvaydov; Nicholas E Geacintov; Vladimir Shafirovich
Journal:  Phys Chem Chem Phys       Date:  2014-05-09       Impact factor: 3.676

10.  Repair efficiency of (5'S)-8,5'-cyclo-2'-deoxyguanosine and (5'S)-8,5'-cyclo-2'-deoxyadenosine depends on the complementary base.

Authors:  Paritosh Pande; Rajat S Das; Clayton Sheppard; Yoke W Kow; Ashis K Basu
Journal:  DNA Repair (Amst)       Date:  2012-10-10
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