Literature DB >> 21219406

Case series on a diversity of illicit weight-reducing agents: from the well known to the unexpected.

Magdalene H Y Tang1, Sammy P L Chen, Sau W Ng, Albert Y W Chan, Tony W L Mak.   

Abstract

AIMS: To provide an overview of illicit weight-reducing agents found in over-the-counter slimming products ingested by poisoned patients.
METHODS: The clinical details and analytical findings of slimming products involved in poisoning cases between 2004 and 2009 were reviewed.
RESULTS: Sixty-six (including one fatal) poisoning cases were encountered. Eighty-one products were analysed and found to contain undeclared prescription weight-loss drugs, drug analogues, banned drugs, drugs used for an inappropriate indication or animal thyroid tissue, with up to six illicit agents within the same product. Many products were readily available from shops or the Internet.
CONCLUSIONS: A rich diversity of illicit, potentially harmful weight-reducing agents was found in over-the-counter slimming products.
© 2011 The Authors. British Journal of Clinical Pharmacology © 2011 The British Pharmacological Society.

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Year:  2011        PMID: 21219406      PMCID: PMC3040546          DOI: 10.1111/j.1365-2125.2010.03822.x

Source DB:  PubMed          Journal:  Br J Clin Pharmacol        ISSN: 0306-5251            Impact factor:   4.335


  10 in total

1.  Risks associated with herbal slimming remedies.

Authors:  C Corns; K Metcalfe
Journal:  J R Soc Promot Health       Date:  2002-12

2.  Homeopathic products, not as innocent and safe as they seem? A case report.

Authors:  Luc J M Mortelmans; Linda Biesemans; Paul Van Rossom
Journal:  Eur J Emerg Med       Date:  2004-08       Impact factor: 2.799

3.  Myocardial infarction induced by appetite suppressants in Malaysia.

Authors:  Shah M Azarisman; Yahya A Magdi; Saidin Noorfaizan; Maskon Oteh
Journal:  N Engl J Med       Date:  2007-11-01       Impact factor: 91.245

4.  Chinese slimming capsules containing sibutramine sold over the Internet: a case series.

Authors:  Dieter Müller; Wolfgang Weinmann; Maren Hermanns-Clausen
Journal:  Dtsch Arztebl Int       Date:  2009-03-27       Impact factor: 5.594

5.  Determination of synthetic drugs used to adulterate botanical dietary supplements using QTRAP LC-MS/MS.

Authors:  Y Chen; L Zhao; F Lu; Y Yu; Y Chai; Y Wu
Journal:  Food Addit Contam Part A Chem Anal Control Expo Risk Assess       Date:  2009-05

6.  Poisoning severity score. Grading of acute poisoning.

Authors:  H E Persson; G K Sjöberg; J A Haines; J Pronczuk de Garbino
Journal:  J Toxicol Clin Toxicol       Date:  1998

7.  Thyrotoxicosis caused by weight-reducing herbal medicines.

Authors:  Hidemi Ohye; Shuji Fukata; Maki Kanoh; Sumihisa Kubota; Kanji Kuma; Akira Miyauchi; Masahiro Sugawara
Journal:  Arch Intern Med       Date:  2005-04-25

8.  Hepatic injury in 12 patients taking the herbal weight loss AIDS Chaso or Onshido.

Authors:  Masayuki Adachi; Hidetsugu Saito; Hisashi Kobayashi; Yoshinori Horie; Shinzo Kato; Masahiro Yoshioka; Hiromasa Ishii
Journal:  Ann Intern Med       Date:  2003-09-16       Impact factor: 25.391

9.  Analogues of erectile dysfunction drugs: an under-recognised threat.

Authors:  W T Poon; Y H Lam; C K Lai; Albert Y W Chan; Tony W L Mak
Journal:  Hong Kong Med J       Date:  2007-10       Impact factor: 2.227

Review 10.  An assessment of the safety and efficacy of sibutramine, an anti-obesity drug with a novel mechanism of action.

Authors:  E Nisoli; M O Carruba
Journal:  Obes Rev       Date:  2000-10       Impact factor: 9.213

  10 in total
  7 in total

1.  Drug treatment for obesity in the post-sibutramine era.

Authors:  Bernard M Y Cheung
Journal:  Drug Saf       Date:  2011-08-01       Impact factor: 5.606

2.  Adulteration of proprietary Chinese medicines and health products with undeclared drugs: experience of a tertiary toxicology laboratory in Hong Kong.

Authors:  Chor Kwan Ching; Sammy Pak Lam Chen; Hencher Han Chih Lee; Ying Hoo Lam; Sau Wah Ng; Mo Lung Chen; Magdalene Huen Yin Tang; Suzanne Suk San Chan; Candy Wai Yan Ng; Jana Wing Lan Cheung; Tina Yee Ching Chan; Nike Kwai Cheung Lau; Yeow Kuan Chong; Tony Wing Lai Mak
Journal:  Br J Clin Pharmacol       Date:  2017-10-04       Impact factor: 4.335

3.  Prioritized Dietary Supplement Information Needs of 307 NCAA Division I Student Athletes.

Authors:  Sarah Osterman; Virginia B Gray; Michelle Loy; Alaina B Coffey; Kelly Smallwood; Michelle T Barrack
Journal:  J Nutr Educ Behav       Date:  2020-02-12       Impact factor: 3.045

4.  Use of a pharmaceutically adulterated dietary supplement, Pai You Guo, among Brazilian-born women in the United States.

Authors:  Pieter A Cohen; Carly Benner; Danny McCormick
Journal:  J Gen Intern Med       Date:  2011-08-16       Impact factor: 5.128

5.  Herbal weight loss pill overdose: sibutramine hidden in pepper pill.

Authors:  Gul Pamukcu Gunaydin; Nurettin Ozgur Dogan; Sevcan Levent; Gulhan Kurtoglu Celik
Journal:  Case Rep Emerg Med       Date:  2015-03-11

6.  A case of dilated cardiomyopathy with massive left ventricular thrombus after use of a sibutramine-containing slimming product.

Authors:  Seung Hye Heo; Min-Ho Kang
Journal:  Korean Circ J       Date:  2013-09-30       Impact factor: 3.243

7.  Cardiovascular Safety Pharmacology of Sibutramine.

Authors:  Jaesuk Yun; Eunyong Chung; Ki Hwan Choi; Dae Hyun Cho; Yun Jeong Song; Kyoung Moon Han; Hey Jin Cha; Ji Soon Shin; Won-Keun Seong; Young-Hoon Kim; Hyung Soo Kim
Journal:  Biomol Ther (Seoul)       Date:  2015-07-01       Impact factor: 4.634

  7 in total

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