Literature DB >> 21215363

Cancer genomes evolve by pulverizing single chromosomes.

Matthew Meyerson1, David Pellman.   

Abstract

A report in this issue describes "chromothripsis," a new mechanism for genetic instability in cancer cells. Chromothripsis appears to be a cataclysmic event in which a single chromosome is fragmented and then reassembled. The phenomenon raises important questions of how chromosome rearrangements can be confined to defined genome segments. Copyright Â
© 2011 Elsevier Inc. All rights reserved.

Entities:  

Year:  2011        PMID： 21215363     DOI： 10.1016/j.cell.2010.12.025

Source DB:  PubMed          Journal:  Cell        ISSN： 0092-8674            Impact factor:   41.582


  39 in total

1.  Chromothripsis: breakage-fusion-bridge over and over again.

Authors:  Carlos Oscar Sánchez Sorzano; Alberto Pascual-Montano; Ainhoa Sánchez de Diego; Carlos Martínez-A; Karel H M van Wely
Journal:  Cell Cycle       Date:  2013-06-11       Impact factor: 4.534

Review 2.  Mechanisms and Consequences of Double-Strand DNA Break Formation in Chromatin.

Authors:  Wendy J Cannan; David S Pederson
Journal:  J Cell Physiol       Date:  2016-01       Impact factor: 6.384

3.  Pathways to chromothripsis.

Authors:  Robert Ivkov; Fred Bunz
Journal:  Cell Cycle       Date:  2015-07-15       Impact factor: 4.534

4.  Genome sequencing of pediatric medulloblastoma links catastrophic DNA rearrangements with TP53 mutations.

Authors:  Tobias Rausch; David T W Jones; Marc Zapatka; Adrian M Stütz; Thomas Zichner; Joachim Weischenfeldt; Natalie Jäger; Marc Remke; David Shih; Paul A Northcott; Elke Pfaff; Jelena Tica; Qi Wang; Luca Massimi; Hendrik Witt; Sebastian Bender; Sabrina Pleier; Huriye Cin; Cynthia Hawkins; Christian Beck; Andreas von Deimling; Volkmar Hans; Benedikt Brors; Roland Eils; Wolfram Scheurlen; Jonathon Blake; Vladimir Benes; Andreas E Kulozik; Olaf Witt; Dianna Martin; Cindy Zhang; Rinnat Porat; Diana M Merino; Jonathan Wasserman; Nada Jabado; Adam Fontebasso; Lars Bullinger; Frank G Rücker; Konstanze Döhner; Hartmut Döhner; Jan Koster; Jan J Molenaar; Rogier Versteeg; Marcel Kool; Uri Tabori; David Malkin; Andrey Korshunov; Michael D Taylor; Peter Lichter; Stefan M Pfister; Jan O Korbel
Journal:  Cell       Date:  2012-01-20       Impact factor: 41.582

5.  Losing control: cancer's catastrophic transition.

Authors:  Indika Rajapakse; David Scalzo; Mark Groudine
Journal:  Nucleus       Date:  2011-07-01       Impact factor: 4.197

Review 6.  Chromothripsis and cancer: causes and consequences of chromosome shattering.

Authors:  Josep V Forment; Abderrahmane Kaidi; Stephen P Jackson
Journal:  Nat Rev Cancer       Date:  2012-09-13       Impact factor: 60.716

Review 7.  Chromosomal instability and cancer: a complex relationship with therapeutic potential.

Authors:  Samuel F Bakhoum; Duane A Compton
Journal:  J Clin Invest       Date:  2012-04-02       Impact factor: 14.808

8.  Whole-genome sequencing reveals complex chromosome rearrangement disrupting NIPBL in infant with Cornelia de Lange syndrome.

Authors:  Morasha Plesser Duvdevani; Maria Pettersson; Jesper Eisfeldt; Ortal Avraham; Judith Dagan; Ayala Frumkin; James R Lupski; Anna Lindstrand; Tamar Harel
Journal:  Am J Med Genet A       Date:  2020-03-03       Impact factor: 2.802

9.  Induction of endocycles represses apoptosis independently of differentiation and predisposes cells to genome instability.

Authors:  Christiane Hassel; Bingqing Zhang; Michael Dixon; Brian R Calvi
Journal:  Development       Date:  2013-11-27       Impact factor: 6.868

10.  Chromoanagenesis and cancer: mechanisms and consequences of localized, complex chromosomal rearrangements.

Authors:  Andrew J Holland; Don W Cleveland
Journal:  Nat Med       Date:  2012-11-07       Impact factor: 53.440
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.