Literature DB >> 21211700

Potential impact of vaginal microbicides on HIV risk among women with primary heterosexual partners.

James M McMahon1, Kathleen M Morrow, Margaret Weeks, Dianne Morrison-Beedy, Amanda Coyle.   

Abstract

This article explores the potential public health consequences of anti-HIV microbicide adoption among women in high-risk communities, using data from an exploratory study to illustrate key points. A brief quantitative survey was administered to 71 drug-using women with primary heterosexual partners in New York City. Only 37% of women reported recent condom use with a primary male partner. A total of 86% expressed willingness to use a microbicide with a primary partner. Among women using condoms, 50% believed they would decrease condom use if they started using a vaginal microbicide. Although overall condom use and intended condom migration was low among women with HIV-infected partners, universal promotion of microbicides could nonetheless lead to an increase in HIV risk among specific subgroups of women, indicating the importance of promoting continued condom use. Further research is needed to inform public policy decisions before the availability of the first commercial microbicide. Copyright Â
© 2011 Association of Nurses in AIDS Care. Published by Elsevier Inc. All rights reserved.

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Year:  2010        PMID: 21211700      PMCID: PMC3050650          DOI: 10.1016/j.jana.2010.05.001

Source DB:  PubMed          Journal:  J Assoc Nurses AIDS Care        ISSN: 1055-3290            Impact factor:   1.354


  19 in total

1.  Women at risk for HIV from a primary partner: balancing risk and intimacy.

Authors:  A O'Leary
Journal:  Annu Rev Sex Res       Date:  2000

2.  Microbicides to prevent heterosexual transmission of HIV: ten years down the road.

Authors:  Janneke van de Wijgert; Christiana Coggins
Journal:  BETA       Date:  2002

3.  Microbicides and HIV: help or hindrance?

Authors:  Eran Karmon; Malcolm Potts; Wayne M Getz
Journal:  J Acquir Immune Defic Syndr       Date:  2003-09-01       Impact factor: 3.731

Review 4.  HIV type 1 transmission probabilities: estimates from epidemiological studies.

Authors:  T D Mastro; D Kitayaporn
Journal:  AIDS Res Hum Retroviruses       Date:  1998-10       Impact factor: 2.205

Review 5.  HIV/AIDS in women: an expanding epidemic.

Authors:  Thomas C Quinn; Julie Overbaugh
Journal:  Science       Date:  2005-06-10       Impact factor: 47.728

6.  Female-to-male transmission of human immunodeficiency virus.

Authors:  N S Padian; S C Shiboski; N P Jewell
Journal:  JAMA       Date:  1991-09-25       Impact factor: 56.272

Review 7.  Shifts in condom use following microbicide introduction: should we be concerned?

Authors:  Anna M Foss; Peter T Vickerman; Lori Heise; Charlotte H Watts
Journal:  AIDS       Date:  2003-05-23       Impact factor: 4.177

Review 8.  Microbicides and HIV prevention: lessons from the past, looking to the future.

Authors:  Georgina C Morris; Charles J N Lacey
Journal:  Curr Opin Infect Dis       Date:  2010-02       Impact factor: 4.915

Review 9.  Heterosexual risk of HIV-1 infection per sexual act: systematic review and meta-analysis of observational studies.

Authors:  Marie-Claude Boily; Rebecca F Baggaley; Lei Wang; Benoit Masse; Richard G White; Richard J Hayes; Michel Alary
Journal:  Lancet Infect Dis       Date:  2009-02       Impact factor: 25.071

10.  Acceptability of Carraguard, a candidate microbicide and methyl cellulose placebo vaginal gels among HIV-positive women and men in Durban, South Africa.

Authors:  Gita Ramjee; Neetha S Morar; Sarah Braunstein; Barbara Friedland; Heidi Jones; Janneke van de Wijgert
Journal:  AIDS Res Ther       Date:  2007-09-27       Impact factor: 2.250

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  4 in total

Review 1.  Human microbiome and HIV/AIDS.

Authors:  Deepak Saxena; Yihong Li; Liying Yang; Zhiheng Pei; Michael Poles; William R Abrams; Daniel Malamud
Journal:  Curr HIV/AIDS Rep       Date:  2012-03       Impact factor: 5.071

2.  Women's perspectives on female-initiated barrier methods for the prevention of HIV in the context of methamphetamine use and partner violence.

Authors:  Jamila K Stockman; Jennifer L Syvertsen; Angela M Robertson; Natasha T Ludwig-Barron; Julie N Bergmann; Lawrence A Palinkas
Journal:  Womens Health Issues       Date:  2014-05-14

Review 3.  Are dual-method messages undermining STI/HIV prevention?

Authors:  Ann O'Leary
Journal:  Infect Dis Obstet Gynecol       Date:  2011-11-15

4.  Condom migration after introduction of pre-exposure prophylaxis among HIV-uninfected adolescents in South Africa: A cohort analysis.

Authors:  Lennart P Maljaars; Katherine Gill; Philip J Smith; Glenda E Gray; Janan J Dietrich; Gabriela B Gomez; Linda-Gail Bekker
Journal:  South Afr J HIV Med       Date:  2017-09-21       Impact factor: 2.744

  4 in total

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