| Literature DB >> 21208926 |
Katherine B Gibney1, Robert S Lanciotti, James J Sejvar, C Thomas Nugent, Jeffrey M Linnen, Mark J Delorey, Jennifer A Lehman, Erin N Boswell, J Erin Staples, Marc Fischer.
Abstract
West Nile virus (WNV) causes an acute infection that is usually cleared by an effective immune response after several days of viremia. However, a recent study detected WNV RNA in the urine of 5 of 25 persons (20%) tested several years after their initial acute WNV disease. We evaluated an established cohort of 40 persons >6 years after initial infection with WNV. Urine collected from all participants tested negative for WNV RNA by reverse-transcription polymerase chain reaction and transcription-mediated amplification. Prospective studies are needed to determine if and for how long WNV persists in urine following WNV disease.Entities:
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Year: 2010 PMID: 21208926 PMCID: PMC3071119 DOI: 10.1093/infdis/jiq057
Source DB: PubMed Journal: J Infect Dis ISSN: 0022-1899 Impact factor: 5.226