| Literature DB >> 15772329 |
Jessica H Tonry1, Shu-Yuan Xiao, Marina Siirin, Hongli Chen, Amelia P A Travassos da Rosa, Robert B Tesh.
Abstract
Adult hamsters that survived experimental West Nile virus (WNV) infection developed persistent viruria. Infectious WNV could be cultured from their urine for up to 52 days. Immunohistochemical examination of kidneys of viruric animals showed foci of WNV antigen in renal tubular epithelial and vascular endothelial cells. These findings are compatible with virus replication and persistent infection of renal epithelial cells. The potential clinical and virologic significance of these findings as well as their possible epidemiologic importance are discussed.Entities:
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Year: 2005 PMID: 15772329
Source DB: PubMed Journal: Am J Trop Med Hyg ISSN: 0002-9637 Impact factor: 2.345