Literature DB >> 21208809

Association of macrophage migration inhibitory factor (MIF) polymorphisms with risk of meningitis from Streptococcus pneumoniae.

Sarah Doernberg1, Bernhard Schaaf, Klaus Dalhoff, Lin Leng, Anna Beitin, Vincent Quagliarello, Richard Bucala.   

Abstract

Macrophage migration inhibitory factor (MIF) is an upstream proinflammatory cytokine encoded by a functionally polymorphic locus. This study of 119 patients explored the potential relationship between MIF genotype and invasive Streptococcus pneumoniae infections. We observed an association between a high-expression MIF allele and occurrence of pneumococcal meningitis.
Copyright © 2010 Elsevier Ltd. All rights reserved.

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Year:  2011        PMID： 21208809      PMCID： PMC3033983          DOI： 10.1016/j.cyto.2010.12.010

Source DB:  PubMed          Journal:  Cytokine        ISSN： 1043-4666            Impact factor:   3.861


  15 in total

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