| Literature DB >> 21207335 |
Dmitriy Nikolavasky1, Klaudia Stangel-Wójcikiewicz, Malgorzata Stec, Michael B Chancellor.
Abstract
The main urinary continence mechanism in human is the striated muscle rhabdosphincter that forms a ring around the mid-urethra. Cellular therapy and the use of stem cells transplanted into the site of the rhabdosphincter in a setting of stress urinary incontinence (SUI) may augment sphincter regeneration. Implanted cells may also release trophic factors promoting muscle and nerve integration into this muscle. We review the use of cellular therapy for SUI and our experience with the development of muscle-derived stem cells.Entities:
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Year: 2011 PMID: 21207335 DOI: 10.1055/s-0030-1268705
Source DB: PubMed Journal: Semin Reprod Med ISSN: 1526-4564 Impact factor: 1.303